Molecular Cell Biology
The cytoskeleton is responsible for mechanical stabilisation of the cell, for its motility and intracellular transport processes as well as for maintenance and change of its overall shape. The research group Molecular Cell Biology focusses on one specific part of the so called cytoskeleton: the actin cytoskeleton. The dynamics and turnover of filaments of the actin cytoskeleton are particularly relevant for effective immune responses, and are also frequently targeted by pathogens. Understanding the molecular mechanisms mediating assembly and disassembly of this filament system is thus among the main goals of Klemens Rottner and his team.
Klemens Rottner studied Zoology/Biology at Paris-Lodron-University Salzburg and after graduation, he continued with his PhD studies in the field of Cell Biology/Immunology. In 2000, he moved to Braunschweig and worked as postdoc in the Department for Cell Biology at the formerly called German Research Centre for Biotechnology (GBF). In 2004, he became head of the research group Cytoskeleton Dynamics at the Helmholtz Centre for Infection Research. In 2010, he was called as professor and head of the Research Unit Actin Dynamics and Motility to the Rheinische Friedrich-Wilhelms-University in Bonn (Institute for Genetics), but returned to Braunschweig in 2014.
Since then he operates as professor at the Institute for Zoology at the TU Braunschweig and additionally heads the research group of Molecular Cell Biology at the Helmholtz-Centre for Infection Research.