Microbial Drugs

The majority of the medically important antibiotic drugs are derived from secondary metabolites, which are produced by bacteria and filamentous fungi. Despite intensive world-wide efforts using alternative approaches, no other concept could so far surpass the historically successful strategy to exploit biologically active natural products as candidates for anti-infective drugs. The recently observed, increasing resistance of the human pathogens against antibiotics has prompted us to intensify our search for novel lead structures from microorganisms and fungi, which can be used as anti-infective drugs.

Leader

Team

Prof Dr Marc Stadler

Head of Department

Publications

  1. Da Cruz ACR, Gusmão LFP, Castañeda-Ruiz RF, Stadler M, Minter DW (2012) Zelodactylaria, an interesting new genus from semi-arid northeast Brazil. Mycotaxon 119: 241-248.
  2. Castañeda-Ruiz RF, Heredia G , Arias-Mota RM, Stadler M, Saikawa M, McKenzie EHC (2012) Two new fungi from Mexico: Anaseptoidium gen. nov. and Cylindrosympodium sosae sp. nov. Mycotaxon 119: 141-148.
  3. Castañeda-Ruiz RF, Heredia G , Arias RM, McKenzie EHC, Hyde KD, Stadler M, Saikawa M, Gené J, Guarro J, Iturriaga T, Minter DW, Crous PW (2011). A new species and re-disposed taxa in Repetophragma. Mycosphere 2: 273-289.
  4. Garcia R, Pistorius D, Stadler M, Müller R (2011) Chemo-phylogeny of myxobacteria as an approach to discover polyunsaturated Omega-3/6 fatty acids. J. Bacteriology 19: 1930-1942
  5. Rachid S, Huo L, Herrmann J, Stadler M, Köpcke B, Bitzer J, Müller R (2011) Mining the cinnabaramide biosynthetic pathway to generate novel proteasome inhibitors. ChemBioChem 12: 922-931.
  6. Engels B, Heinig U, Grothe T, Stadler M, Jennewein S (2011) Cloning and characterization of an Armillaria gallica cDNA encoding protoilludene synthase, which catalyzes the first committed step in the synthesis of antimicrobial melleolides. J. Biol. Chem. 286: 6871-6878.
  7. Fournier J, Flessa F, Peršoh D, Stadler M (2011) Three new Xylaria species from Southwestern Europe. Mycol. Progr. 10: 33-52.
  8. Garcia R, Gerth K, Stadler M, Dogma Jr. IJ, Müller R (2010) Expanded phylogeny of myxobacteria and evidence for cultivation of the 'unculturables'. Mol. Phylogenet. Evol. 57: 878-997.
  9. Silvera-Simón C, Gené J, Guarro J, Castañeda Ruíz RF, Minter DW, Stadler M (2010) A new species of Paradendryphiopsis from Portugal. Mycotaxon 114: 473-479.
  10. Castañeda Ruíz RF, Minter DW, Stadler M, Gené J, Guarro J, Cano J (2010) Two new anamorphic fungi from Cuba: Endophragmiella profusa sp. nov. and Repetoblastiella olivacea gen. & sp. nov. Mycotaxon 113: 415-422.
  11. Fournier J, Köpcke B, Stadler M (2010) New species of Hypoxylon from Western Europe and Ethiopia. Mycotaxon 113: 209-235.
  12. Stadler M, Fournier J, Gardt S, Peršoh D (2010) The phylogenetic position of Rhopalostroma as inferred from a polythetic approach. Persoonia 25: 11-21.
  13. Castañeda Ruíz RF, Heredia Abarca G, Arias Mota RM, Becerra Jernandez CI, Stadler M, Saikawa M, Minter DW (2010) Anaselenosporella sylvatica gen. & sp. nov. and Pseudoacrodictys aquatica sp. nov., two new anamorphic fungi from Mexico. Mycotaxon 112: 65-74.
  14. Castañeda Ruíz RF, Morillo O, Tovar B, Hernández Z, Iturriaga T, Minter DW Gené J, Guarro J, Stadler M (2010) Endogenospora, a new genus of anamorphic fungi from Venezuela. Mycotaxon 112: 75-82.
  15. Læssøe T, Srikitikulchai P, Fournier J, Köpcke B, Stadler M (2010) Lepraric acid derivatives as chemotaxonomic markers in Hypoxylon aeruginosum, Chlorostroma subcubisporum and C. cyaninum, sp. nov. Fungal Biology 114: 481-489.
  16. Stadler M, Fournier J, Læssøe T, Decock C, Peršoh D, Rambold G (2010) Ruwenzoria, a new genus of the Xylariaceae from Central Africa. Mycol. Progr. 9: 169-179.
  17. Stadler M, Fournier J, Læssøe T, Chlebicki A, Lechat C, Flessa F, Rambold G, Peršoh D (2010) Chemotaxonomic and phylogenetic studies of Thamnomyces (Xylariaceae). Mycoscience 51: 189-207.
  18. Castañeda Ruíz RF, Heredia Abarca G, Arias Mota RM, Becerra CI, Saikawa M, Minter DW, Stadler M (2010) Elotespora, an enigmatic anamorphic fungus from Tabasco, Mexico. Mycotaxon 111: 197-203.
  19. Fournier J, Stadler M, Hyde KD, Duong LM (2010). The genus Rostrohypoxylon and two new Annulohypoxylon species from Northern Thailand. Fungal Diversity 40: 23-36
  20. Castañeda Ruíz RF, Pascholati Gusmão LF, Oliveira de Moraes Jr V, Heredia Abarca G, Saikawa M, Minter DW, Stadler M (2009) Two setose anamorphic fungi: Ampullicephala gen. nov. and Venustosynnema grandiae sp. nov. Mycotaxon 109: 275-288.
  21. 23. Peršoh D, Melcher M, Graf K, Fournier J, Stadler M, Rambold G (2009) Molecular and morphological evidence for the delimitation of Xylaria hypoxylon. Mycologia 101: 256-268.
  22. Castañeda Ruíz RF, Guerrero B, Adamo GM, Morillo O, Minter DW, Stadler M, Gené J, Guarro J (2009). A new species of Selenosporella and two microfungi recorded from cloud forest in Mérida, Venezuela. Mycotaxon 109: 63-74. 2009.
  23. Castañeda Ruíz RF, Pascholati Gusmão LF, Rodrigues da Cruz AC, Heredia Abarca G, Iturriaga T, Guarro J, Saikawa M, Stadler M, Minter DW (2009) Phaeocandelabrum, a new genus of anamorphic fungi to accommodate Sopagraha elegans and two new species, Ph. callisporum and Ph. concinnum. Mycotaxon 109: 221-232.
  24. Castañeda Ruíz RF, Iturriaga T, Heredia Abarca G, Minter DW, Gené J, Stadler M, Saikawa M, Silvera-Simón C (2009) Notes on Heteroconium and a new species from Venezuela. Mycotaxon 107: 225-237.
  25. Bitzer J, Læssøe T, Fournier J, Kummer V, Decock C, Tichy HV, Piepenbring M, Peršoh D, Stadler M (2008) Affinities of Phylacia and the daldinoid Xylariaceae, inferred from chemotypes of cultures and ribosomal DNA sequences. Mycol. Res. 112: 251-270.
  26. Stadler M, Fournier J, Læssøe T, Lechat C, Tichy HV, Piepenbring M (2008). Recognition of hypoxyloid and xylarioid Entonaema species from a comparison of holomorphic morphology, HPLC profiles, and ribosomal DNA sequences. Mycol. Progr. 7: 53-73.
  27. Stadler M, Fournier J, Beltrán-Tejera E, Granmo A (2008) The "red Hypoxylons" of the temperate and subtropical Northern Hemisphere. In "A Festschrift in honor of Professor Jack D. Rogers (Glawe DA, Ammirati JF, eds.). North American Fungi 3: 73-125.
  28. Vasilyeva L, Stadler M (2008) Pyrenomycetes of the Russian Far East 3. Three new Daldinia species (Xylariaceae). Mycotaxon 104: 284-296.
  29. Möhrle V, Stadler M, Eberz G (2007) Biosensor-guided screening for macrolides. Analyt. Bioanalyt. Chem. 388: 1117-1125.
  30. Stadler M, Mayer-Bartschmid A, Seip S, Bitzer J, Müller H, Benet-Buchholz J, Gantner F, Tichy HV, Reinemer P, Bacon KB (2007) Cinnabaramides A-G, lactacystin and salinosporamide analogues from a terrestrial Streptomyces species. J. Nat. Prod. 70: 246-252.
  31. Stadler M, Fournier J, Quang DN, Akulov AY (2007) Metabolomic studies on the chemical ecology of the Xylariaceae (Ascomycota). Nat. Prod. Comm. 2: 287-304.
  32. Castañeda Ruiz RF, Heredia Abarca G, Arias RM, Saikawa M, Minter DW, Stadler M (2007) Anamorphic fungi from submerged plant material: Phaeomonilia pleiomorpha, P. corticola and Cacumisporium pleuroconidiophorum. Mycotaxon 100: 327-336.
  33. Bitzer J, Köpcke B, Stadler M, Hellwig V, Ju YM, Seip S, Henkel T (2007) Accelerated dereplication of natural products, supported by reference libraries. Chimia 51: 332-338.
  34. Heredia Abarca G, Castañeda Ruiz RF, Arias RM, Saikawa M, Stadler M (2007) Anamorphic fungi from submerged plant material: Acumispora verruculosa, Pleurophragmium aquaticum, and P. miniumbonatum. Mycotaxon 101:89-97.
  35. Castañeda Ruiz RF, Pascholati Gusmão LF, Guarro J, Stchigel AM, Stadler M, Saikawa M (2007). Two new anamorphic fungi from Brazil: Cacumisporium tropicale and Acrodictys irregularis. Mycotaxon 102: 91-99.
  36. Castañeda Ruiz RF, Pascholati Gusmão LF, Guarro J, Stchigel AM, Stadler M, Saikawa M, Leão-Ferreira SM (2007). Two new anamorphic fungi from Brazil: Dictyochaetopsis polysetosa and Myrothecium compactum. Mycotaxon 103: 1-8.
  37. Quang DN, Stadler M, Fournier J, Tomita A, Hashimoto T (2006) Cohaerins C-F, four azaphilones from the xylariaceous fungus Annulohypoxylon cohaerens. Tetrahedron 62: 6349-6354.
  38. Stadler M, Quang DN, Tomita A, Hashimoto T, Asakawa Y (2006) Production of bioactive metabolites during stromatal ontogeny of Hypoxylon fragiforme. Mycol. Res. 110: 811-820.
  39. Castañeda Ruiz RF, Minter DW, Stadler M, Saikawa M, Camino-Vilaró M (2006) Anamorphic fungi from submerged leaves in Cuba: Brevicatenospora enteroproliferata gen. et sp. nov. and Beltraniopsis aquatica sp. nov. Mycotaxon 96: 151-158.
  40. Quang DN, Stadler M, Fournier J, Asakawa Y (2006) Carneic acids A and B, two chemotaxonomically significant antimicrobial agents from the xylariaceous ascomycete, Hypoxylon carneum. J. Nat. Prod. 69: 1198-1202.
  41. Quang DN, Hashimoto T, Stadler M, Asakawa Y (2005) Dimeric azaphilones from the xylariaceous ascomycete Hypoxylon rutilum. Tetrahedron 61: 8451-8455.
  42. Hellwig V, Ju YM, Rogers JD, Fournier J, Stadler M (2005) Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling. Mycol. Progr. 4: 39 - 54.
  43. Stadler M, Læssøe T, Vasilyeva L (2005) The genus Pyrenomyxa and its affinities to other cleistocarpous Hypoxyloideae as inferred from morphological and chemical traits. Mycologia 97: 1129-1139.
  44. Triebel D, Persoh D, Wollweber H, Stadler M (2005) Phylogenetic relationships among Daldinia, Entonaema and Hypoxylon as inferred from ITS nrDNA sequences. Nova Hedw. 80: 25-43.
  45. Quang DN, Hashimoto T, Radulovic N, Fournier J, Stadler M, Asakawa Y (2005) Sassafrins A-D, new antimicrobial azaphilones from the fungus Creosphaeria sassafras. Tetrahedron 61: 1743-1748.
  46. Quang DN, Hashimoto T, Nomura Y, Wollweber H, Hellwig V, Fournier J, Stadler M, Asakawa Y (2005) Cohaerins A and B, azaphilones from the fungus Hypoxylon cohaerens, and comparison of HPLC-based metabolite profiles in Hypoxylon sect. Annulata. Phytochemistry 65: 797-809.
  47. Castañeda Ruiz RF, Heredia G, Arias RM, Stadler M, Minter DW (2005) Two Hyphomycetes from submerged plant material of México. Mycotaxon 91: 333-337.
  48. Castañeda Ruiz RF, Stadler M, Saikawa M., Iturriaga T, Decock C, Heredia G (2005) Microfungi from submerged plant material: Zelotriadelphia amoena gen. et sp. nov. and Vanakripa fasciata sp. nov. Mycotaxon 91: 339-345.
  49. Quang DN, Hashimoto T, Radulović N, Stadler M, Asakawa Y. (2005). Antimicrobial azaphilones from the xylariaceous inedible mushrooms. Int. J. Medicinal Mushrooms 7: 452-455.
  50. Quang, DN, Hashimoto T, Stadler M, Radulovic N, Asakawa Y (2005) Antimicrobial azaphilones from the fungus Hypoxylon multiforme. Planta Med. 71: 1058-1072.
  51. Stadler M., Hellwig V, Mayer-Bartschmid A, Denzer D, Wiese B, Burkhardt N (2005) Novel analgesic triglycerides from cultures of Agaricus macrosporus and other basidiomycetes as selective inhibitors of Neurolysin. J. Antibiot. 58: 775-786.
  52. Quang DN, Hashimoto T, Tanaka M, Stadler M, Asakawa Y (2004) Cyclic azaphilones daldinins E and F from the ascomycete fungus Hypoxylon fuscum (Xylariaceae). Phytochemistry 65: 469-473.
  53. Stadler M, Ju YM, Rogers JD (2004) Chemotaxonomy of Entonaema, Rhopalostroma and other Xylariaceae. Mycol. Res. 108: 239-256.
  54. Stadler M, Wollweber H, Jäger W, Briegert M, Venturella G, Castro JM, Tichy HV (2004) Cryptic species related to Daldinia concentrica and D. eschscholzii, with notes on D. bakeri. Mycol. Res. 108: 257-273.
  55. Castañeda Ruiz RF, Heredia G, Arias RM, Saikawa M., Minter DW, tadler M, Guarro J, Decock C (2004) Two new Hyphomycetes from rainforests of México, and Briansuttonia, a new genus to accommodate Corynespora alternarioides. Mycotaxon 89: 297-306.
  56. Stadler M, Læssøe T, Simpson JA, Wollweber H (2004) A survey of Daldinia species with large ascospores. Mycol. Res. 108: 1025-1041.
  57. Quang DN, Hashimoto T, Tanaka M, Stadler M, Asakawa Y (2004) Constituents of the inedible mushroom Hypoxylon rubiginosum. J. Nat. Prod. 67: 1152-1155.
  58. Stadler M, Wollweber H, Fournier J (2004) A host-specific species of Hypoxylon from France, and notes on the chemotaxonomy of the "Hypoxylon rubiginosum complex". Mycotaxon 90: 187-211.
  59. Hellwig V, Wittka R, Mauler F, Freitag J, Liu J, Ding ZH, Stadler M (2003) Activities of prenylphenol derivatives from fruitbodies of Albatrellus spp. on the human vanilloid receptor 1 (VR1) and characterisation of the novel natural product, confluentin. Arch. Pharm. Med. Chem. 336: 119-126.
  60. Stadler M, Tichy HV, Katsiou E, Hellwig V (2003) Chemotaxonomy of Pochonia and other conidial fungi with Verticillium-like anamorphs. Mycol. Progr. 2: 95-122.
  61. Hellwig V, Mayer-Bartschmid A, Greif G, Kleymann G, Zitzmann W, Tichy HV, Stadler M (2003) Pochonins A-F, Antiviral and antiparasitic resorcylic acid lactones from Pochonia chlamydosporia var. catenulata. J. Nat. Prod. 66: 829-837.
  62. Stadler M, Baumgartner M, Ide K, Popp A, Wollweber H (2002) Importance of ascospore ornamentation in the taxonomy of Daldinia. Mycol. Progr. 1: 31-42.
  63. Hellwig V, Grothe T, Mayer-Bartschmid A, Endermann R, Geschke FU, Henkel T, Stadler M (2002) Altersetin, a new antibiotic from cultures of endophytic Alternaria spp. Taxonomy, fermentation, isolation, structure elucidation, and biological activities. J. Antibiot. 55: 881-892.
  64. Quang DN, Hashimoto T, Tanaka M, Baumgartner M, Stadler M, Asakawa Y (2002) Concentricols B, C and D, three novel squalene-type triterpenoids from the ascomycete Daldinia concentrica. Phytochemistry 61: 345-353.
  65. Mühlbauer A, Triebel D, Persoh D, Wollweber H, Seip S, Stadler M (2002) Macrocarpones, novel metabolites from stromata of Hypoxylon macrocarpum and new evidence on the chemotaxonomy of Hypoxylon. Mycol. Progr. 1: 235-248.
  66. Quang DN, Hashimoto T, Tanaka M, Baumgartner M, Stadler M, Asakawa Y (2002) Chemical constituents of the ascomycete Daldinia concentrica. J. Nat. Prod. 65: 1869-1874.
  67. Stadler M, Wollweber H, Mühlbauer A, Henkel T, Wollweber H, Asakawa Y, Hashimoto T, Rogers JD, Ju YM, Wetzstein HG, Tichy HV (2001) Secondary metabolite profiles, genetic fingerprints and taxonomy of Daldinia and allies. Mycotaxon 77: 379-429.
  68. Stadler M, Baumgartner M, Grothe T, Mühlbauer A, Seip S, Wollweber H (2001) Concentricol, a taxonomically significant triterpenoid from Daldinia concentrica. Phytochemistry 56: 787-793.
  69. Wollweber H, Stadler M (2001) Zur Kenntnis der Gattung Daldinia in Deutschland und Europa. Z. Mykol. 67: 3-53.
  70. Stadler M, Baumgartner M, Wollweber H, Rogers JD, Ju YM (2001) Daldinia decipiens sp. nov. and notes on some other European Daldinia spp. inhabiting Betulaceae. Mycotaxon 80: 167-177.
  71. Stadler M, Baumgartner M, Wollweber H (2001) Three new Daldinia species with yellow stromatal pigments. Mycotaxon 80: 179-196.
  72. Stadler M, Bauch F, Henkel T, Mühlbauer A, Müller H, Spaltmann F, Weber K (2001) Antifungal actinomycete metabolites discovered in a differential cell-based screening using a recombinant TOPO1 deletion mutant strain. Arch. Pharm. Med. Chem. 334: 143-147.
  73. Stadler M, Wollweber H, Mühlbauer A, Asakawa Y, Hashimoto T, Rogers JD, Ju YM, Wetzstein HG, Tichy HV (2001) Molecular chemotaxonomy of Daldinia and other Xylariaceae. Mycol. Res. 105: 1191-1205.
  74. Wetzstein HG, Stadler M, Tichy HV, Dalhoff A, Karl W (1999) Degradation of Ciprofloxacin by basidiomyceteous fungi and identification of metabolites generated by the brown rot fungus Gloeophyllum striatum. Appl. Environ. Microbiol. 66: 1556-1563.
  75. Dekermendijan K, Shan R, Nielsen M, Stadler M, Sterner O. Witt M-R (1998) The affinity to the brain dopamine D1 receptor in vitro of triprenyl phenols isolated from the fruit-bodies of Albatrellus ovinus. Europ. J. Med. Chem. 32: 351-356.
  76. Stadler M, Sterner O (1998) Production of bioactive secondary metabolites in the fruit-bodies of macrofungi as a response to injury. Phytochemistry 49: 1013-1019.
  77. Stadler M, Henkel T, Müller H, Weber K, Schlecker H (1998) Identification of alkaloids and polyketides in an actinomycete by a combination of analytical and preparative HPLC and spectroscopic methods. J. Chromatography 818A: 187-195.
  78. Shan R, Stadler M, Anke H, Sterner O (1997) The reactivity of the fungal toxin papyracillic acid. Tetrahedron 53: 6209-6214.
  79. Shan R, Stadler M, Anke H, Sterner O (1997) Novel naphthalenone and phthalide metabolites from Lachnum papyraceum. J. Nat. Prod. 60: 804-805.
  80. Stadler M, Fouron J-Y, Anke H, Sterner O (1996) 1,2-Dihydroxymintlactone, a new nematicidal monoterpene from the basidiomycete Cheimonophyllum candidissimum. Z. Naturf. 50c : 473-475.
  81. Stadler M, Anke H, Dekermendijan K, Reiss R, Sterner O, Witt M-R (1996) New azaphilones from fruit bodies and mycelial cultures of the ascomycete Bulgaria inquinans Fr. Nat. Prod. Lett. 7: 7-14.
  82. Shan R, Stadler M, Sterner O, Anke H (1996) New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum. VIII. Isolation, structure determination and biological activities of minor metabolites structurally related to mycorrhizin A. J. Antibiot. 49: 447-452.
  83. Shan R, Anke H, Stadler M, Sterner O (1996) Papyracillic Acid, a new penicillic acid analogue from the Ascomycete Lachnum papyraceum. Tetrahedron 52: 10249-10254.
  84. Stadler M, Anke H, Sterner O (1995) New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum. III. Production of halogenated isocoumarin derivatives, isolation and biological activities. J. Antibiot. 48: 261-266.
  85. Stadler M, Anke H, Sterner O (1995) New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum. IV. Structural elucidation of novel isocoumarin derivatives. J. Antibiot. 48: 267-270.
  86. Stadler M, Anke H, Sterner O (1995) New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum. V. Production, isolation and biological activities of bromine-containing mycorrhizins and lachnumons and four other new bioactive metabolites. J. Antibiot. 48: 149-153.
  87. Stadler M, Anke H, Shan R, Sterner O (1995) New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum. VI. Structure determination of non-halogenated metabolites related to mycorrhizin A. J. Antibiot. 48: 154-157.
  88. Stadler M, Anke H, Sterner O (1995) New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum. VII. Structure determination of brominated metabolites related to mycorrhizin A and lachnumon. J. Antibiot. 48: 158-161.
  89. Stadler M, Anke H, Sterner O (1995) The structure determination of six new nematicidal bisabolanes from the fungus Cheimonophyllum candidissimum. Tetrahedron 50: 12649-12654.
  90. Anke H, Stadler M, Mayer A, Sterner O (1995) Secondary metabolites with nematicidal activities from nematophagous fungi and ascomycetes. Can. J. Bot. 73 Suppl 1: S932-S939.
  91. Stadler M, Dagne E, Anke H (1994) Nematicidal and other biological activities of isoflavonoid type phytoalexins from Taverniera abyssinica. Planta Med. 60: 550-552.
  92. Stadler M, Anke H, Sterner O (1994) New nematicidal and antimicrobial compounds from the basidiomycete Cheimonophyllum candidissimum (Berk et Curt.) Sing.: I. Producing organism, fermentation, isolation of active compounds and biological activities. J. Antibiot. 47: 1284-1289.
  93. Stadler M, Anke H, Sterner O (1993) Linoleic acid, the nematicidal principle of nematophagous fungi. Arch. Microbiol. 160: 401-405.
  94. Stadler M, Anke T, Dasenbrock J, Steglich W (1993) Phellodonic acid, a new biologically active hirsutane derivative from Phellodon melaleucus (Thelephoraceae, Basidiomycetes). Z. Naturforsch. 48c: 545-549.
  95. Sterner O, Anke H, Bergquist K-E, Sheldrick WS, Stadler M, Mayer A, Sundin A (1993) The structure determination of panellon and panellol, two 14-noreudesmanes isolated from Resupinatus leightonii. Tetrahedron 49: 7519-7524.
  96. Stadler M, Anke H, Arendholz W-R, Hansske F, Anders U, Bergquist K-E, Sterner O (1993) Lachnumon and lachnumol A, new metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum. I. Fermentation, isolation and biological activities. J. Antibiot. 46: 961-967.
  97. Stadler M, Anke H, Bergquist K-E, Sterner O (1993) Lachnumon and lachnumol A, new metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum. II. Structural elucidation. J. Antibiot. 46: 968-972.
  98. Stadler M, Anke H, Sterner O (1993) New biologically active compounds from the nematode-trapping fungus Arthrobotrys oligospora Fres. Z. Naturforsch. 48c: 843-850.
  99. Stadler M, Mayer A, Sheldrick WS, Sterner O, Bergquist K-E, Sundin A, Anke H (1992) Biologically active compounds from Basidiomycetes: Panellon and dihydropanellon from Resupinatus leightonii. In Behrens D Driesel AJ (eds.): DECHEMA Biotechnology Conferences, Vol. 5B, VCH Weinheim, Germany, pp. 721-724.
  100. Dagne E, Abate D, Stadler M, Anke H, Sterner O (1991) Biologically active compounds from diverse sources. In Dagne E (ed.) Proceedings of the 4th NAPRECA Symposium on the Chemistry of Natural Products, Addis Ababa, Ethiopia, pp. 14-18.

Reviews, Opinion Articles & book chapters

  1. Stadler M (2011) Importance of secondary metabolites in the Xylariaceae as parameters for assessment of their taxonomy, phylogeny, and functional biodiversity. Current Research in Environmental & Applied Mycology 1: 75-133.
  2. Stadler M (2010) Book review of "Alternaria: an identification manual. By Emory G. Simmons". Mycotaxon 110: 535-538.
  3. Stadler M, Schulz B (2009) High energy biofuel from endophytic fungi? Trends in Plant Science 14: 353-355
  4. Stadler M, Keller NP (2008) Paradigm shifts in fungal secondary metabolite research. Editorial to special issue. Mycol. Res. 112: 127-130 (Special issue covering entire volume 112(2) of Mycol. Res.).
  5. Stadler M, Fournier J (2006) Pigment chemistry, taxonomy and phylogeny of the Hypoxyloideae (Xylariaceae). Rev. Iberoam. Micol. 23: 160-170.
  6. Stadler M, Hellwig V (2005) Chemotaxonomy of the Xylariaceae and remarkable bioactive compounds from Xylariales and their associated asexual stages. Recent Res. Devel. Phytochem. 9: 41-93.
  7. Stadler M, Hellwig V (2004) PCR-based data and secondary metabolites as chemotaxonomic markers in HTS for bioactive compounds from fungi. In An, Z (ed.) Handbook of Industrial Mycology. Marcel Dekker, New York, pp. 269-307.

Mycology

Natural Product Chemistry

Fermentation

Microbial Strain Collection

Guests and former members

Over the past years, our department has become a training centre for young researchers who came to the HZI from all over Germany, Europe and other continents.

Former PhD students (including guests; if they graduated abroad or at other German research facilities, the universities/institutes where they were working are listed)

Dr. Kevin Becker

https://www.scopus.com/authid/detail.uri?authorId=57203983531

Dr. Samad Ashrafi (JKI Braunschweig)

https://www.scopus.com/authid/detail.uri?authorId=56376369700

Dr. Amelie Glemser

https://www.researchgate.net/profile/Amelie-Glemser

Dr. Lilibeth Chaverra-Munoz

https://www.scopus.com/authid/detail.uri?authorId=57205703399

Dr. Tian Cheng

https://www.scopus.com/authid/detail.uri?authorId=57200618210

Dr. Clara Chepkirui

https://www.scopus.com/authid/detail.uri?authorId=57191512092

Dr. Boontiya Chuankind (Mae Fah Luang University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=57203999176

Dinushani Anupama Daranagama

https://www.scopus.com/authid/detail.uri?authorId=56436667800

Sandra Halecker

https://www.scopus.com/authid/detail.uri?authorId=56100561300

Dr. Khadija Hassan

https://www.scopus.com/authid/detail.uri?authorId=57223933186

Sae Kanaki (former BSc student)

https://www.scopus.com/authid/detail.uri?authorId=57201120169

Dr. Sarunpron Khruengsai (Mae Fah Luang University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=57208059889

Dr. Wilawan Kuephadungphan (Prince of Songkla University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=57194599410

Dr. Eric Kuhnert

https://www.scopus.com/authid/detail.uri?authorId=55711117800

Dr. Sebastian Lopez-Fernandez

https://www.scopus.com/authid/detail.uri?authorId=58332210500

Dr. Ausana Mapook (Mae Fah Luang University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=55984885800

Dr.  Lucky Mulwa

https://www.scopus.com/authid/detail.uri?authorId=57201089726

Dana Nedder (former MSc student)

https://www.scopus.com/authid/detail.uri?authorId=57909360100

Maira Michehl (former BSc student)

https://www.scopus.com/authid/detail.uri?authorId=57208547387

Dr. Nico Mitschke (former MSc student)

https://www.scopus.com/authid/detail.uri?authorId=57194775733

Dr. Abolfazl Narmani Kordlar

https://www.scopus.com/authid/detail.uri?authorId=55577177000

Dr. Allen G. Niego (Mae Fah Luang University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=57194589053

Dr. Sarah Raouia Noumeur (Univ. Batna, Algeria)

https://www.scopus.com/authid/detail.uri?authorId=57192706285

Dr. Pathompong Paomephan (Mahidol University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=57190839836

Associate Prof. Dr. Chayanard Phukhamsakda (Mae Fah Luang University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=56663217400

Kunthida Gift Phutthacharoen

Dr. Mohammad Javad Pourmoghaddam

https://www.scopus.com/authid/detail.uri?authorId=57214091702

Dr. Gian Primahana

https://www.scopus.com/authid/detail.uri?authorId=57200047825

Dr. Monique Rascher

https://www.scopus.com/authid/detail.uri?authorId=57191329035

Dr. Christian Richter

https://www.researchgate.net/profile/Christian-Richter-10/research

Dr. Milan Samarakoon (Chiang Mai University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=57194189277

Dr. Zeljka Rupcic

https://www.scopus.com/authid/detail.uri?authorId=57191328786

Dr. Lulu Shao

https://www.scopus.com/authid/detail.uri?authorId=57212510174

Chutima Tanapichatsakul (Mae Fah Luang University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=57197754876

Dr. Esteban B. Sir (Universidad de Buenos Aires)

https://www.scopus.com/authid/detail.uri?authorId=55768990200

Dr. Benjarong (Zine) Thongbai (Mae Fah Luang University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=55940744700

Dr. Naritsada Thongklang (Mae Fah Luang University, Thailand)

https://www.scopus.com/authid/detail.uri?authorId=54997948600

Dr. Lucile Wendt

https://www.scopus.com/authid/detail.uri?authorId=56754857700

Former postdocs and guest PhD students (including researchers funded by AvH, DAAD and other grants)

Dr. Adela Cmokova

https://www.scopus.com/authid/detail.uri?authorId=56120956600

Dr. Güner Ekiz

https://www.scopus.com/authid/detail.uri?authorId=55922281800

Prof. Dr. Soleiman Helaly (†)

https://www.scopus.com/authid/detail.uri?authorId=35118897900

Dr. Stephan Hüttel

https://www.scopus.com/authid/detail.uri?authorId=57195363421

Dr. Lili Jia

https://www.scopus.com/authid/detail.uri?authorId=57209258668

Prof. Dr. Allan Patrick Macabeo

https://www.scopus.com/authid/detail.uri?authorId=8632579600

Dr. Ashaimaa Y. Moussa

https://www.scopus.com/authid/detail.uri?authorId=55038572000

Dr. Kathrin I. Mohr

https://www.scopus.com/authid/detail.uri?authorId=12774474800

M.Sc. Chitwadee Phithakrotchanakoon

https://www.scopus.com/authid/detail.uri?authorId=25638715800

Dr. Sara Rodrigo

https://www.scopus.com/authid/detail.uri?authorId=55443450900

Dr. Enge Sudarman

https://www.scopus.com/authid/detail.uri?authorId=14029509100

Prof. Dr. Rémy Bertrand Teponno

https://www.scopus.com/authid/detail.uri?authorId=1300510400

Dr. Vincent Wiebach

https://www.scopus.com/authid/detail.uri?authorId=56682133300

Dr. Kathrin Wittstein

https://www.scopus.com/authid/detail.uri?authorId=36515782700

Former technical staff

Burkhard Ebert

Simone Heitkämper

Christel Kakoschke

Kerstin Schobert

Romy Vogel

Philine Wotsch

Story: New drugs from fungi

HZI researchers traveled to Yaoundé, Cameroon, for a workshop on the collection, culture and identification of fungal strains. A new research hub will strengthen natural product research in fungi in the country. [read more]

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  • How do researchers at the HZI and HIPS develop antibiotic candidates from natural products?

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