Human-Microbe Systems Bioinformatics
The human body encompasses fewer human cells than microbes. They constantly interact with each other and the host and greatly affect an individual's health and well-being. In our group, we develop and apply state-of-the-art bioinformatics software to study the human-microbe systems and aim to discover natural products involved in communication between the two realms. This group is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS).
We bridge computational and experimental science to develop researcher-friendly bioinformatics tools that advance natural product discovery.
Alexey Gurevich studied software engineering at St. Petersburg State Polytechnic University (BSc 2010, summa cum laude) and St. Petersburg Academic University of the Russian Academy of Sciences (MSc 2012, summa cum laude). In 2011, in the Prof. Pavel Pevzner group at the Academic University, he started focussing on algorithmic bioinformatics. The group later relocated to St. Petersburg State University where Alexey obtained a Ph.D. in bioinformatics in 2018. He worked at St. Petersburg University until 2022 with short research visits to the Pevzner lab at the University of California San Diego (2015 and 2016) and to the Kohlbacher lab at the University of Tübingen (2019, DAAD Fellowship). In July 2022, Alexey joined HIPS as a Junior Professor leading the Human-Microbe Systems Bioinformatics group.
Alexey's research focuses on creating efficient algorithms and software for handling noisy omics data. He contributed to the state-of-the-art SPAdes and QUAST genome assembly and analysis software and multiple computational methods for natural product discovery. For these works, he received the Web of Science Highly Cited Researcher Russia Award in 2018.