Genome Mining for Secondary Metabolites

The misuse of antibiotics on a global scale has led to an ever-growing antibiotic resistance crisis. Novel antimicrobial compounds are urgently needed. Microorganisms are considered to be one of the most prolific sources for natural product drugs including antibiotics. Developing novel genome mining approaches to harness the potential of the underexplored biosynthetic gene pathways and discover novel microbial natural products, is a potential antibiotic resistance crisis mitigation path. This group is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

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