Pollen Mimetic Transcutaneous Vaccination
In cooperation with Claus-Michael Lehr and Steffi Hansen of the Helmholtz Institute for Pharmaceutical Research in Saarland our group will develop and test a vaccine platform based on nanoparticles that mimic pollen, which has been shown to be able to penetrate the skin through hair follicles. The nanoparticle will burst upon contact with human sweat, releasing the cargo of adjuvants and antigens, thereby specifically targeting the dendritic cells that surround hair follicles.
This project is funded by Grand Challenges Explorations initiative of the Bill & Melinda Gates foundation.
Helmholtz Institute for Pharmaceutical Research, Saarland
- Vaccinology and applied Microbiology- Prof. Dr. Carlos A. Guzmán