A study to prevent infectious diseases in children (project concluded)
We conducted a prospective cohort study during a period of four months in the winter period 2014/2015 and recruited children aged 0 to 6 years in day care centers in Braunschweig, Lower Saxony, Germany. Our study focused on the incidence of infections and the use of measures to prevent infections. We collected information on the prevention measures through a self-administered questionnaire. A subsample of the study population focused on the transmission of respiratory and gastrointestinal infections within families. In this prospective subsample, the participants (typically one of the parents) kept a diary of infection episodes for all household members and nasal swabs were collected in case of respiratory infection symptoms. In the main sample, only retrospective data on the number of infections of the household members were collected (and no bio samples were obtained). Participants could volunteer for either of the study groups. In addition to this, participants could participate in a module on early childhood caries (ECC), in which they filled in a questionnaire on oral hygiene, and teeth swabs were taken to investigate the bacterial composition of healthy and diseased teeth.
Schlinkmann KM, Bakuli A, Mikolajczyk R. Incidence and comparison of retrospective and prospective data on respiratory and gastrointestinal infections in German households. BMC Infect Dis. 2017;17(1):336.
This project was initiated by the group "Epidemiological and Statistical Methods" and lead by Prof. Dr. Rafael Mikolajczyk until July 2017.
Prof. Dr. Refael Mikolajczyk
- Epidemiology- Prof. Dr. Gérard Krause
HZI - Helmholtz Centre for Infection Research