Research Projects (Third party funds)


Evaluation of the Tuberculosis Surveillance System in Ghana using a Capture-Recapture Design

Under-registration and under-notification of tuberculosis (TB) cases has implications for TB control as it leads to the accumulation of undetected infected individuals who then become a threat to society. There exist inconsistencies in TB case detection estimates between national survey results and what is notified to the National TB Control Programme (NTP). The national TB prevalence survey conducted in 2014 among the general population in Ghana has revealed a threefold higher TB burden than WHO estimates suggest. The national survey revealed a pool of TB cases in the population, but only 35% are currently being detected.

This study aims at making use of a capture-recapture method to evaluate the completeness of TB case registration data by conducting audit of 3 levels of data collection sources including laboratory, health facility, district and sub-district TB registry data. The study also aims to collect primary data from pharmacies and over-the-counter medicine sellers through telephone interview to assess their contribution to TB case detection in Ghana.

We will use retrospective data of TB patients to investigate the gaps in the TB surveillance system and identify where the surveillance system is likely to miss cases. In addition, we will study the factors influencing private pharmacies to refer people with TB-like symptoms for diagnosis at general health care facilities which we hope will provide high quality data to the National TB control programme for further optimization of their work.

The study is scheduled for implementation in 2018 and 2019 in the Eastern Region of Ghana.

The Statement of Informed Consent from the Study Protocol is found here.

PhD student involved

Ms. Mavis Pearl Kwabla (PhD programme "Epidemiology")


  • Ghanaian-German Postgraduate Training Programme (DAAD)
  • HZI 



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