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Here you can find out more about the scientific results of the HZI in the research topics ”Bacterial and Viral Pathogens”, “Immune Response and Interventions” and “Anti-Infectives”.
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The coronaviruses are a family of viruses that includes a series of very different pathogens. These viruses usually infect mammals, rodents, and birds, but only few coronaviruses adapted to humans. They did this with great success: About one third of all typical "common colds" and some cases of diarrhoea as well are caused by these RNA Viruses, which are the largest of their kind. We have compiled more information about the coronaviruses for you.
With the pathogen SARS-CoV-2, a novel virus that can cause respiratory diseases and pneumonia has been spreading worldwide since the end of 2019. Here we will keep you informed about current developments in research and provide answers to the most important questions.
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Essentially, we are never alone – because they are always with us: billions of microorganisms – such as bacteria, viruses or fungi – inhabit our bodies. They live on our skin, in our mouths, noses or intestines – depending on the preferences of our tiny cohabitants and the demands they make of their environment. “For the most part, the microbiota consists of bacteria that are…
Yersinia pseudotuberculosis is a microbe that causes food poisoning and is considered a parent of Yersinia pestis, the causative agent of the plague. To cause disease, it uses a toxin named cytotoxic necrotizing factor (CNF) by its ability to cause necrosis when injected into the skin. Several pathogenic strains of Escherichia coli also produce CNF. “Despite different pathogenic…
Control of the coronavirus pandemic by vaccines, which are currently close to approval, is not expected until later in 2021. Until then, SARS-CoV-2 case numbers must be controlled through non-pharmaceutical measures such as contact reductions, hygiene measures and case tracking. A recent statement calls for these measures to be coordinated across Europe. This is to avoid repeated…
In the biosafety level 3 suite at HIRI, the scientists infected human cells with the new coronavirus, which uses RNA as genetic material. In a second step, they purified the viral RNA and identified the proteins bound to it. "Mass spectrometry allows us to accurately determine the host proteins that directly associate with the viral genome. In this particular case, we were able to…
“I am very pleased about the great honour for Rolf Müller and the recognition of his many years of research work. I would like to congratulate him very warmly on behalf of the entire HZI,” said Prof Dirk Heinz, Scientific Director of the HZI. “Rolf Müller is one of the world's most recognised natural product researchers and has made essential contributions to combating bacterial…