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Here you can find out more about the scientific results of the HZI in the research topics ”Bacterial and Viral Pathogens”, “Immune Response and Interventions” and “Anti-Infectives”.
The coronaviruses are a family of viruses that includes a series of very different pathogens. These viruses usually infect mammals, rodents, and birds, but only few coronaviruses adapted to humans. They did this with great success: About one third of all typical "common colds" and some cases of diarrhoea as well are caused by these RNA Viruses, which are the largest of their kind. We have compiled more information about the coronaviruses for you.
With the pathogen SARS-CoV-2, a novel virus that can cause respiratory diseases and pneumonia has been spreading worldwide since the end of 2019. Here we will keep you informed about current developments in research and provide answers to the most important questions.
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The research team from the TU Braunschweig and the HZI succeeded in generating the antibodies to SARS-CoV-2 in vitro using antibody phage display technology. This was based on the existing HAL9/10 antibody gene library, and for the best-performing antibodies, the researchers additionally mapped the binding sites to the virus and modeled the corresponding molecular interaction…
CoVerage enables evaluation of epidemiological dynamics of different SARS-CoV-2 variants
This is where the CoVerage web resource comes in. It can be used to identify particularly successful SARS-COV-2 lines and predict their further spread, taking epidemiological information into account. The evaluation provided by CoVerage also makes it possible to draw conclusions about…
If, for example, policymakers want to open up cultural services and the service sector in general, it would be advisable to make the reopening contingent on rapid antigen testing plans, adapted hygiene concepts, and digital data collection. Since this approach would avoid infections, adopting it would be in the best interests of providers of cultural and other services.
T cell precursors originate in the bone marrow and mature in the thymus. They then circulate through the bloodstream and secondary lymphoid tissues in search of foreign or altered proteins. Tissue-resident T cells are a subset of T lymphocytes that have left the bloodstream and settled in tissues. These immune cells can remain there for a long time. A new training network called…
SORMAS (Abkürzung für „Surveillance Outbreak Response Management and Analysis System“) wurde vom Helmholtz-Zentrum für Infektionsforschung (HZI) entwickelt und ist nach einer Analyse der Johns-Hopkins-Universität eines der international erfolgreichsten digitalen Systeme für das Fall- und Kontaktpersonenmanagement bei COVID-19. Ein speziell für Gesundheitsämter im Rahmen der…