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2019-06-20
”To develop bottromycins further, the producing bacteria need to be persuaded to make new versions of bottromycin that have improved properties,“ says Jun.-Prof. Jesko Köhnke, who heads the junior research group ”Structural Biology of Biosynthetic Enzymes“ at HIPS. For this, however, the scientists must first understand how the complicated chemical reactions during the formation of…
2019-04-11
With few antibiotics in development since the early 1990s, antimicrobial resistance (AMR) is a major and rapidly growing global health challenge that is already making previously easy to treat infections harder to treat. Approximately 700,000 people worldwide die of drug-resistant infections every year and this number is expected to increase significantly in the future.2…
2019-04-04
“HZI and Technische Universität Braunschweig celebrate the award of the Inhoffen Medal which is given in recognition of world-leading research in the field of total synthesis of natural agents. In just a short period of time, Phil Baran has revolutionised the synthesis of organic natural compounds and set innovative impulses in synthetic methodology as well," says Prof Peter H.…
2019-03-25
Some 400,000 people around the world succumb to the consequences of a hepatitis C infection each year. The hepatitis C virus is usually transmitted by blood. An infection can remain undetected for long periods of time, because the disease initially progresses largely without symptoms and manifest flu-like symptoms are often not recognised as being related to a hepatitis C infection.…
2019-02-28
The infectious agents Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa are Gram-negative bacteria and much-feared around hospitals. Due to their double cell wall, these germs are difficult to control and are among the most harmful pathogens on the WHO's priority list. Scientists from the Helmholtz Centre for Infection Research (HZI),…
