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2019-10-29
Broadly neutralising antibodies attack multiple strains of a pathogen, neutralise its effect and thus support the immune system, and have already been identified for HIV or influenza viruses, for example. Their special feature is that they bind to conserved molecular structures of the viruses that do not change much, while the pathogen continues to mutate in the organism. This makes…
2019-10-23
Bacteriophages are viruses that infect bacteria by injecting their genetic material into host cells. This DNA is transcribed and translated into proteins that make up new viral particles. Eventually, the bacterial host cell bursts open and releases new bacteriophages. With the help of the CRISPR-Cas system, bacteria can recognize foreign DNA and degrade it before it serves as a…
2019-10-17
Lignin is a component of wood and endows it with its flexibility. For the production of paper, it needs to be removed in order to prevent yellowing and increase the strength of the paper. That leads to large amounts of unwanted lignin, which has been awaiting re-utilization for many years. While this problem has been partially solved by recent methods for the depolymerisation of…
2019-10-11
The human genome contains the information for thousands of lncRNAs. Modern sequencing technologies have shown that a large number of these lncRNAs are activated during infections. “LncRNAs are important regulators of the host response to a pathogen. But how lncRNAs function at the molecular level, which molecules they interact with and how lncRNAs use or influence these interaction…
2019-10-09
A two-day symposium was the centrepiece of the recent visit. Scientists from HZI and McGill University presented their research on selected research topics related to infection including global health, the role of microbiota in infections and personalized medicine. “We were very pleased to welcome the McGill delegation to the HZI. The visit helps us a lot to work out our connecting…
