Tim Bergbrede "An integrated protein production platform to boost academic and translational science projects"
In recent years, standardization and centralization of biological sample generation and analysis has been a trend in global research. Spawned by the pharmaceutical industry and larger structure initiatives, this trend has also reached the academic science sector and given rise to numerous service- and core facilities to date. Biological “tool” production, i.e. the generation of plasmid constructs and recombinant protein samples, is one of the areas where focusing of expertise and resources has led to more efficient workflows, increased throughput and reproducibility in many research facilities. In this presentation, the layout and workflow of a highly automated and parallelized protein production facility will be outlined. Showing some “real life” examples from academia and academic-industrial translational science, I would like to demonstrate how intimately this service platform is connected with other facilities and different entities of its scientific environment. While it is clearly beyond the scope of this overview to provide model solutions for the entire spectrum of protein supply requirements, the selected cases exemplify the capacity of this generic platform layout, which is adaptable to the needs of many different fields of research and, as such, in the best sense enabling science.
Date: 14 July, 14:00 - 15:30
Helmholtz Centre for Infection Research
Building and room
Tim Bergbrede, Max-Planck-Institut, Dortmund