HZI-Symposium "Legionella Spp."

From molecular biology to ecology of waterborne pathogens most relevant in developed countries

  • Overview

    Bacteria of the genus Legionella cause waterborne infections resulting in severe pneumonia. In Europe, 70% of the cases of the so-called Legionnaires’ disease (LD) originate from strains of L. pneumophila serogroup (Sg) 1, 20% from other L. pneumophila serotypes and 10% from other Legionella species. In contrast, in the Middle East most legionella infections are due to L. pneumophila Sg3.

    The overall objective of this project is to advance current knowledge on the ecology of legionella in freshwater systems, the environmental factors affecting their occurrence, virulence potential and infectivity and to understand their transmission to humans.

    We will use an integrated molecular approach based on high-resolution diagnostics of environmental samples and clinical isolates to determine the abundance, activity and virulence potential of Legionella populations in-situ. Combining environmental and molecular epidemiological data, we aim at understanding the link between ecology and population dynamics of legionella and cases of LD. The project will result in a novel understanding of the molecular epidemiology of legionella and provide new surveillance tools and strategies to prevent LD.

    Date: 17.06.2014, 10:00


    Helmholtz-Centre for Infection Research

    Building and room



    Manfred Höfle
    HZI, Braunschweig, Germany

    Antje Flieger
    RKI, Wenigerode, Germany

    Christina Lang
    RKI, Wenigerode,

    Maren Schlegel
    RKI, Wenigerode, Germany

    Janine Rasch
    TU Braunschweig, Germany

    Stefanie Krüger
    TU Braunschweig, Germany

    Julia Hoppe
    TU Braunschweig, Germany

    Christian Lück
    TU Dresden, Germany

    Yehonatan Sharaby
    University Haifa, Israel

    Sara Rodríguez-Martínez
    University Haifa, Israel

    Hila Mizrahi
    University Haifa, Israel

    Malka Halpern
    University Haifa, Israel

    Dina Bitar
    University Al-Quds, Jerusalem, Palestine

    Ashraf Zayed
    Al-Quds University, Jerusalem, Palestine

    Rene Lesnik
    HZI, Braunschweig, Germany

    Marina Pecellin
    HZI, Braunschweig, Germany


    Dina Bitar, University Al-Quds, Jerusalem, Palestine