Intravital Microscopy in Infection and Immunity

Whether or not an infected organism is successful in defending itself against a pathogen depends primarily upon the interaction of the cells within the immune system – both among one another and with the pathogen. The “language” of these interactions, soluble and membrane-linked signal molecules, has been thoroughly examined in recent years. The manner in which these signals are exchanged within the living organism is still unclear. With the aid of specialized microscopy technologies, the interplay between host and pathogen can be tracked nowadays in living tissues.


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