Microbial Drugs

The majority of the medically important antibiotic drugs (including e.g., penicillins, cephalosporins, erythromycin, vancomycin, and daptomycin) are derived from secondary metabolites, which are produced by bacteria and filamentous fungi. Despite intensive world-wide efforts using alternative approaches based on synthetic chemistry, no other concept could so far surpass the historically successful strategy to exploit biologically active natural products as candidates for anti-infective drugs. The recently observed, increasing resistance of the human pathogens against antibiotics has prompted us to intensify our search for novel lead structures from microorganisms and fungi, which can be used as anti-infective drugs.



Dr Rolf Jansen


Curriculum Vitae

since 1980      
scientist at the Helmholtz Center for Infection Research, Dept. Microbial Drugs

1977 – 1980
Dissertation in the group of Prof. Hans Paulsen, Institute of Organic Chemistry,

1970 – 1977
Studies in chemistry, University of Hamburg, (Diplom-Chemiker) University of Hamburg: “Synthesen von Sisomicin B, Sisomicin D und modifizierten Sisomicin-Antibiotika”

1968 – 1970
Studies in biology, University of Hamburg

Isolation, structure elucidation, derivatization, molecular modeling of natural products from bacteria and fungi.



Natural Product Chemistry


Microbial Strain Collection

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