• kinase


    A kinase is…

    Enzyme that attaches a phosphate group to a specific substrate. Kinases play a central role in intracellular signal transduction.

  • knockout mouse


    A knockout mouse is…

    Mouse strain in which a particular gene has been purposely inactivated. From the development and metabolism of these mice, conclusions regarding a particular gene’s or protein’s function can be drawn. Scientists are using knockout mice as animal models for certain human diseases. There are also knockin mice where an additional gene is introduced: in most cases, a mouse gene is replaced by a human one.

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