Neurophysiology/structural biology/microbiology PhD project

Code: -

2019-09-02

SBBE

Tasks

Neurophysiology/structural biology/microbiology PhD project: Bacterial infections targeting synaptic adhesion molecules: effects of bacterial adhesin binding to adhesive components of photoreceptor/retinal synapses

We are looking to recruit a highly motivated PhD student for a joint research project between the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS, Saarbrücken, Germany - a branch of the Helmholtz Centre for Infection Research) and Saarland Medical University (UKS, Homburg, Germany).

The project on bacterial adhesins binding to neuronal structures is highly interdisciplinary and ranges from molecular microbiology/structural biology to neurophysiology and will include bacterial and mammalian protein expression, crystallization studies, synaptic physiology using genetically engineered reporter mice, Ca2+ imaging, cell wall associated proteome studies, and different adhesion assays including single molecule force spectroscopy.

Further information on the three research groups of

Prof. Dr. Schmitz (https://www.uniklinikum-saarland.de/einrichtungen/fachrichtungen/anatomie_zellbiologie_und_entwicklungsbiologie/univ_prof_dr_med_frank_schmitz_anatomie/)

Prof. Dr. Köhnke (https://www.helmholtz-hzi.de/koehnke), and

Prof. Dr. Bischoff (https://www.uniklinikum-saarland.de/einrichtungen/kliniken_institute/infektionsmedizin/medizinische_mikrobiologie_und_hygiene/forschung/)

can be found online.

Prerequisite

The ideal candidate has a MSc degree in Biology (or related) with previous MSc thesis research expertise in neurophysiology, structure biology, and/or microbiology. Willingness to routinely work under biosafety level S2 and with mice is essential.

Related Subjects

  • Medical / Clinical Science
  • Neurophysiology
  • Structural Biology
  • Microbiology
  • Molecular Biology

Location

HIPS Saarbrücken

Research Group

Starting date

The desired starting date is between 11/2019 and 02/2020.

Published on

2019-09-02

Applications accepted until  2019-09-30

Applications are only accepted electronically as a single PDF file containing the relevant information (motivation letter, CV, A-level/BSc/MSc diplomas, transcripts of records, names of 2 references, and, if available, letters of recommendation). Please send them to all three email addresses (Frank.Schmitz@uks.euJesko.Koehnke@helmholtz-hips.de and markus.bischoff@uks.eu) in parallel.

Applications will be continuously reviewed until the position has been filled.

Did you now?

HZI International Graduate School

The HZI International Graduate School for Infection Research (GS-FIRE) provides an innovative structured PhD programme within the field of Infection Research.

PhD programme “Epidemiology”

The PhD programme “Epidemiology” is a three-year doctoral programme in the area of epidemiological research and is coordinated by the Department of Epidemiology of the HZI.

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