PhD position: CRISPR biology and technologies in bacteria

Code: 61/2018



The research group “RNA Synthetic Biology” (RSYN) of Dr. Prof. Chase Beisel at the Helmholtz Institute for RNA-based infection research (HIRI) in Würzburg (Germany) is offering a PhD position: CRISPR biology and technologies in bacteria.


The Helmholtz Institute for RNA-based Infection Research (HIRI) was established in May 2017 as a joint venture between the Helmholtz Centre for Infection Research (HZI) and the Julius-Maximilians-University of Würzburg (JMU). Located on the Würzburg medical campus, it will be the first research institution worldwide to exclusively address the role of ribonucleic acids (RNAs) in infection processes. Based on these findings, the HIRI will pioneer an integrative approach to exploit the vast potential of RNA as a diagnostic, drug, and therapeutic target for new strategies to combat infectious diseases. The RSYN research group started in January 2018. For further information, please visit: or

Project description:

The research group “RNA synthetic biology” invites talented and highly motivated applicants for a PhD position focused on characterizing and harnessing the properties of novel CRISPR-Cas immune systems. CRISPR-Cas systems have offered powerful tools for medicine, biotechnology, and agriculture, yet the full diversity and functions of these systems remain to be explored. The project will focus on characterizing previously unreported systems and using these insights to develop a new generation of CRISPR technologies for genome editing in bacterial pathogens and commensals. More information on current research themes in the research group can be found as part of Prof. Beisel’s profile on the HZI website. Selected students will work in the dynamic environment of the HIRI, which is part of the Helmholtz Centre for Infection Research (HZI).


  • Master’s Degree in biotechnology, biochemistry, microbiology, molecular biology, or a related field of the life sciences or engineering
  • Excellent English communication skills (written and spoken)
  • Ability to work independently and as part of an international team
  • A strong desire to do research, enthusiastic, creative, and highly self-motivated


HIRI Würzburg

The Handicapped

Qualified applicants with a disability will be given preference.

Special preference toward women


Starting date

Any time after 1 December, 2018

Contract time limit

Initial term 1 year, with the possibility of an extension of additional 2 years

Probation period

6 months


alike TVöD E13 (50%) with the possibility of an additional payment of 10%

Published on


Applications accepted until  07.10.2018

Applicants are required to complete the online application form here: (Please refer to the job number 61/2018)

For questions regarding the PhD projects, please contact Dr. Chase Beisel via e-mail at the following address:

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HZI International Graduate School

The HZI International Graduate School for Infection Research (GS-FIRE) provides an innovative structured PhD programme within the field of Infection Research.

PhD programme “Epidemiology”

The PhD programme “Epidemiology” is a three-year doctoral programme in the area of epidemiological research and is coordinated by the Department of Epidemiology of the HZI.

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