Graduate School

The HZI International Graduate School for Infection Research (GS-FIRE) provides an innovative structured PhD programme within the field of Infection Research. Implemented at the campus of the Helmholtz Centre for Infection Research in Braunschweig together with its partner universities GS-FIRE has created an electrifying environment where young researchers are stimulated to exchange knowledge with their colleagues, peers and leading scientists from around the world. Besides intensive scientific training the young researchers have the possibility of improving their soft skills and advancing their interdisciplinary knowledge in preparation for the job market.

HZI Graduate School courses, lectures and symposia

2020

June 16 - 17

Course: Good Scientific Practice
Aim & Content: Good scientific practice, data management, publication practice and authorship, responsible mentoring, cooperation in science and conflicts of interest, scientific misconduct, managing conflicts.
Course Leader: Dr. Michael Gommel; Institute for Systemic Medicine and Organizational Ethics, Berlin

June 3 - 5

First Joint Annual Retreat for all doctoral researchers, HZI Graduate School, Campus HZI Braunschweig

April 30    

Assessment Immunology Lecture
HZI Graduate School

April 28 - 30

Course: Helmholtz Career and Leadership Course
Aim & Content: The aim of this course is to provide postgraduate research students with an opportunity to build their understanding, skills and confidence in the key areas of career planning, career development and the development of their leadership style.
Course Leader: Emma Ford and Mike Rawland, Coatching4Careers, UK

April 27

Immunology Lecture: Immune defence at body surfaces - the gut
Lecturer: Prof. Dr. Till Strowig, HZI Braunschweig

April 27

Immunology Lecture: B cell development and somatic evolution
Lecturer: Prof. Dr. Dunja Bruder, HZI Braunschweig

April 20

Immunology Lecture: Fighting influenza virus within the lung
Lecturer: Prof. Dr. Michael Meyer-Hermann, BRICS Braunschweig

April 7 - 8

Course: Good Scientific Practice
Aim & Content: Good scientific practice, data management, publication practice and authorship, responsible mentoring, cooperation in science and conflicts of interest, scientific misconduct, managing conflicts.
Course Leader: Dr. Julia Verse; Institute for Systemic Medicine and Organizational Ethics, Berlin

March 30

Immunology Lecture: T cell differentation: a delicate balance between inflammatory and regulatory T cells
Lecturer: Dr. Stefan Flöß, HZI Braunschweig

March 23

Immunology Lecture: T cell development, activation and effector functions
Lecturer: Prof. Dr. Jochen Hühn, HZI Braunschweig

March 16

Immunology Lecture: Antigen uptake and processing, dendritic cells; how pathogens (e.g. CMV) try to evade the immune response?
Lecturer: Prof. Dr. Dr. Luka Cicin-Sain, HZI Braunschweig

March 9

Immunology Lecture: Innate immune defense mediated by pattern recognition receptors and viral counteracting strategies
Lecturer: Dr. Markus Stempel, HZI Braunschweig

February 28    

Assessment Medical Microbiology Lecture
HZI Graduate School

February 24

Medical Microbiology Lecture: Phage therapy
Lecturer: Dr. Christine Rohde, DSMZ Braunschweig

February 17 - 21

Lab course: TGE and BEVS Protein Expression in Insect cells
Aim & Content: This course will cover the theory and practical training in the baculoviral expression vector system (BEVS) and virus free transient gene expression (TGE) in insect cells. Additionally, the TGE method will be performed in mammalian HEK293 cells. Basic sterile cell cultivation, transient transfection, amplification of the virus, viral infection and protein expression screens will be part of the training. 
Course Leader: Dr. Joop van den HeuveL, HZI Braunschweig

February 17

Medical Microbiology Lecture: The influence of the microbiota on gastrointestinal infections
Lecturer: Prof. Dr. Till Strowig, HZI Braunschweig

February 10

Medical Microbiology Lecture: Zoonotic infections
Lecturer: Prof. Dr. Peter Valentin-Weigand, TiHo Hannover

February 3

Medical Microbiology Lecture: Mycobacterial infections
Lecturer: Dr. Ralph Goethe, TiHo Hannover

January 27

Medical Microbiology Lecture: Regulation of bacterial virulence
Lecturer: Prof. Dr. Marcus Fulde, FU Berlin

January 20

Medical Microbiology Lecture: Cell-cell communication in oral biofilms
Lecturer: Prof. Dr. Irene Wagner-Döbler, HZI-Braunschweig

January 15

Lecture: Introduction into the HZI Graduate School    
Lecturer: Dr. Berenike Henneberg; HZI Braunschweig

January 13

Medical Microbiology Lecture: Vizualization of pathogenic bacteria and their bacterial interaction structure with electron microscopic methods
Lecturer: Dr. Alejandro Arce, HZI Braunschweig

January 6

Medical Microbiology Lecture: Vizualization of pathogenic bacteria and their bacterial interaction structure with electron microscopic methods
Lecturer: Prof. Dr. Manfred Rohde, HZI Braunschweig

2019

December 13    

Assessment Molecular Biology Lecture
HZI Graduate School

December 9 

Molecular Biology and Mammalian Genetics Lecture: Cellular communication and signal transduction
Lecturer: Dr. Mario Köster, HZI Braunschweig

December 5 

12th International PhD Symposium, HZI Graduate School, Braunschweig

December 2 

Molecular Biology and Mammalian Genetics Lecture: Transgenic mouse models
Lecturer: Dr. Hansjörg Hauser, HZI Braunschweig

November 19

Molecular Biology and Mammalian Genetics Lecture: Cell cycle regulation, proliferation and oncogenesis
Lecturer: Dr. Hansjörg Hauser, HZI Braunschweig

November 11

Molecular Biology and Mammalian Genetics Lecture: Transcriptional regulation and epigenetics
Lecturer: Dr. Mario Köster, HZI Braunschweig

November 4

Molecular Biology and Mammalian Genetics Lecture: Genome integrity and diversification
Lecturer: Prof. Dr. Halyna Shcherbata, MHH Hannover

November 3 - 4

Lab course: Introduction to statistics, not only for biologists 
Aim & Content: Statistics provides methods to analyse and understand the data, to find deviations, correlations, to support or to reject hypothesis.
Statistics is often (mis)understood as a toolbox of methods from which one just has to pick the right one. But without a basic understanding of the underlying statistical concepts, the application of these methods is often of no use and can even produce wrong or misleading results. A biologist does not need to become an expert in statistics. But with a basic intuitive understanding, biologists can carry out standard analyses steps themselves and also know how to talk to statisticians who in most cases know little about biology.
This course is intended to explain the basic concepts and ideas of statistics and how to use the methods provided by statistics. At the end of the course, a hands-on computer lab exercise will be offered in which the participants can apply what they have learned using the open source statistics software R.
Course Leader: Prof. Dr. Frank Klawonn; HZI Braunschweig

October 28

Molecular Biology and Mammalian Genetics Lecture: Genome integrity and diversification
Lecturer: Prof. Dr. Dagmar Wirth, HZI Braunschweig

October 24

Lecture: Introduction into the HZI Graduate School    
Lecturer: Dr. Sabine Kirchhoff; HZI Braunschweig

October 21

Molecular Biology and Mammalian Genetics Lecture: Mouse and human genetics to identify important factors involved in the host response to infections 
Lecturer: Prof. Dr. Klaus Schughart, HZI Braunschweig

October 11    

Assessment Bioinformatics Lecture
HZI Graduate School

October 10 - 11

Course: Plan A - How to plan your career in science
Aim & Content: Science careers are demanding. But the biggest difficulty seems to be that it seems somehow impossible to plan them to the end. On the other hand there are some rules one could use to plan at least the most important steps and to minimize the risks. The workshop will deal with the complete career ladder - from PhD to the appointment to a chair - and will address the most important career steps
Course Leader: Dr. Matthias Schwarzkopf; karriere-beratung-akademiker.de, Jena

October 7 - 8

Course: Plan B - Alternatives to Science Careers    
Aim & Content: At the end of the PhD phase or at the beginning of the postdoctoral phase, the decision must be made, whether the career should be continued up to the professorship or to leave the science system. In general there are many fears before this step, as no alternative career paths have been found or tried before.
The workshop will focus on finding ideas for possible alternative career paths.
For this purpose, a competency profile will be drawn up, which will incorporate the past professional experiences and educational pathways. On the basis of the competency profile, the participants will then consider which potential job and/or job profiles could fit. In addition, the fundamentals of job applications are presented: From the search for positions, through the understanding of tenders, up to the actual application process.
Course Leader: Dr. Matthias Schwarzkopf; karriere-beratung-akademiker.de, Jena

September 30

Bioinformatics Lecture: Algorithms in phylogenetic interference and their application
Lecturer: Thorsten Klingen, BRICS Braunschweig

September 23

Bioinformatics Lecture: Pitfalls in biomarker determination and analysis of high dimensional data
Lecturer: Prof. Dr. Karsten Hiller, TU-Braunschweig

September 19 - 20

Course: Good Scientific Practice
Aim & Content: Good scientific practice, data management, publication practice and authorship, responsible mentoring, cooperation in science and conflicts of interest, scientific misconduct, managing conflicts.
Course Leader: Dr. Michael Gommel; Institute for Systemic Medicine and Organizational Ethics, Berlin

September 16

Bioinformatics Lecture: Structural Dynamics in Prokayotic Genomes Retrieved by 3rd Generation Sequencing
Lecturer: Dr. Boyke Bunk, DSMZ Braunschweig

September 9

Bioinformatics Lecture: A use case of machine learning for clinical data analysis: cytokines as predictors for virological relapse in hepatitis B infections
Lecturer: Dr. Juan Carlos Lopez Alfonso, BRICS Braunschweig

September 2

Bioinformatics Lecture: PRODORIC2 - a database about gene regulation in prokaryotes
Lecturer: Dr. Andreas Bremges, HZI Braunschweig

August 26

Bioinformatics Lecture: Discovering genetic determinants of gene expression levels with RNA-seq
Lecturer: Dr. David DeLuca, MHH Hannover

August 19

Bioinformatics Lecture: Integration of multi-omics data for understanding immune functions
Lecturer: Prof. Dr. Yang Li; CiiM Hannover

August 12

Bioinformatics Lecture: (Mis-)Use of hypothesis testing
Lecturer: Prof. Dr. Frank Klawonn; HZI Braunschweig

August 12

Lecture: Introduction into the HZI Graduate School    
Lecturer: Dr. Sabine Kirchhoff; HZI Braunschweig

August 8

Career opportunities in the pharmaceutical industry: Regulatory affairs – Pharmacovigilance – Clinical research
Aim & Content: The course starts with an overview pharmaceutical industry in Germany. Three fields of work within the pharmaceutical industry are presented.
The questions what additional knowledge should I have in addition to my expertise, and how to find job opportunities and companies that fit to me will be discussed.
Course Leader: Dr. Christian Strobe, Regulatory Affairs/Compliance Manager, Nordmark Arzneimittel GmbH, Uetersen, Germany

August 2    

Assessment Biology of Actinobacteria and Myxobacteria Lecture
HZI Graduate School
 

July 29

Biology of Actinobacteria and Myxobacteria Lecture: Biology of Myxobacteria
Lecturer: PD Dr. Joachim Wink; HZI Braunschweig

July 22

Biology of Actinobacteria and Myxobacteria Lecture: Pathogenity of Actinobacteria
Lecturer: PD Dr. Joachim Wink; HZI Braunschweig

July 15

Biology of Actinobacteria and Myxobacteria Lecture: Isolation and biotechnological aspects of Actinobacteria
Lecturer: PD Dr. Joachim Wink; HZI Braunschweig

July12

Career Opportunity Workshop: Insight into her successful career
Lecturer: Prof. Dr. Maren von Koeckritz-Blickwede, Biochemistry of Infection, University of Veterinary Medicine Hannover, Foundation

July 9 - 10

Course: Applied Intercultural Communication
Aim & Content: An Introduction to Intercultural Communication for Doctoral Students: Developing Key Problem-Solving Skills for the International Workplace.
Course Leader: Alexia Petersen, M.A., Aachen

July 8

Biology of Actinobacteria and Myxobacteria Lecture: Polyphasic Taxonomy
Lecturer: PD Dr. Joachim Wink; HZI Braunschweig

July 4

Symposium: A Day on “Career Opportunities”, HZI Braunschweig
Alumni of the Helmholtz International Graduate School for Infection Research present their careers.

June 24

Biology of Actinobacteria and Myxobacteria Lecture: Biology of Actinobacteria and their secondary metabolites
Lecturer: PD Dr. Joachim Wink; HZI Braunschweig

June 17

Biology of Actinobacteria and Myxobacteria Lecture: Antibiotics
Lecturer: PD Dr. Joachim Wink; HZI Braunschweig

June 12

Career Opportunity Workshop: From infection biologist to Medical Director in Pharma
Lecturer: Dr. Sven Baumann, Medical Director / Prokurist, INDIVIOR Deutschland GmbH

June 7    

Assessment Structural Biology Lecture
HZI Graduate School

May 27

Structural Biology Lecture: Structure-based drug discovery

May 20

Structural Biology Lecture: Binding affinity and more

May 15 - 16

10th Annual Retreat, HZI Graduate School, Haus der Wissenschaft Braunschweig

May 13

Structural Biology Lecture: Validation and interpretation of protein structures


May 6

Structural Biology Lecture: Basics of NMR spectroscopy

April 29

Structural Biology Lecture: Basics of EM (& Small Angle X-Ray Scattering, SAXS)

April 15

Structural Biology Lecture: Basics of X-ray crystallography

April 12

Lecture: Introduction into the HZI Graduate School 

April 8 - 9

Course: Good Scientific Practice
Aim & Content: Good scientific practice, data management, publication practice and authorship, responsible mentoring, cooperation in science and conflicts of interest, scientific misconduct, managing conflicts.
Course Leader: Dr. Julia Verse; Institute for Systemic Medicine and Organizational Ethics, Berlin

April 8

Structural Biology Lecture: Protein expression

April 3

Course: Statistics in day-to-day research work
Aim & Content: On the basis, of experimental scenarios, typical problems of statistically supported experimental design will be explained and some basics of statistic will be discussed. 
• Statistical Terminology and Basics: Population and Sample, Mean, Quantiles, Standarddeviation
• The Concepts of Hypothesis Testing: Simple t-test, 2-Sample t-test
• ANOVA: Comparison of more than 2 Groups
• Regression analysis: Modeling Relationships between Continuous Variables

April 1

Structural Biology Lecture: Structure and function of biomacromolecules

March 29 

Assessment Epidemiology Lecture
HZI Graduate School

March 25

Epidemiology Lecture: Field trip to NAKO study centre at CRC, Hannover 
Lecturer: Dr. Yvonne Kemmling; CRC Hannover

March 18-22

Lab course: Mikrobiology of Myxobacteria and Actinobacteria 
Aim & Content: Antibiotic active secondary metabolites from Myxobacteria and Actinobacteria, characterization of producing strains, identification of biological active compounds, isolation of new strains from different habitats.
Course Leader: Dr. Kathrin Mohr and PD Dr. Joachim Wink; HZI Braunschweig

March 18

Epidemiology Lecture: Modelling in Infectious Disease Epidemiology
Lecturer: Dr. Stephan Glöckner; HZI Braunschweig

March 11

Epidemiology Lecture: Case study and SurvStat 
Lecturer: Minh Tam Nguyen; HZI Braunschweig

March 4

Epidemiology Lecture: Bias and Confounding
Lecturer: Daniela Gornyk; HZI Braunschweig

February 25 – March 1

Lab course: TGE and BEVS Protein Expression in Insect cells 
Aim & Content: This course will cover the theory and practical training in the baculoviral expression vector system and virus free transient gene expression in insect cells. Basic sterile cell cultivation, transient transfection, amplification of the virus, viral infection and protein expression screens will be part of the training. The course will take around 40 hours during the week. Due to the intensive training at the bench, there will be only place for 3 groups of 3 people. The course is primarily aimed for PhD students, post docs and members of the CSSB who plan to use the technology in their research project.
Course Leader: Dr. Joop van den Heuvel; HZI Braunschweig

Contact

Dr. Sabine Kirchhoff

GS-FIRE (International Graduate School for Infection Research)

Helmholtz Centre for Infection Research
Inhoffenstraße 7
38124 Braunschweig

hzigrad.school@helmholtz-hzi.de

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