Postdoctoral position: “New RNA-seq approaches and single-cell RNA-seq”.
The department “RNA-Biology of Bacterial Infection” of Prof. Jörg Vogel at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg (Germany) is offering a Postdoctoral position: “New RNA-seq approaches and single-cell RNA-seq”. The Helmholtz Institute for RNA-based Infection Research (HIRI) was established in May 2017 as a joint venture between the Helmholtz Centre for Infection Research (HZI) and the Julius-Maximilians-University of Würzburg (JMU). Located on the Würzburg medical campus, it will be the first research institution worldwide to exclusively address the role of ribonucleic acids (RNAs) in infection processes. Based on these findings, the HIRI will pioneer an integrative approach to exploit the vast potential of RNA as a diagnostic, drug, and therapeutic target for new strategies to combat infectious diseases. www.helmholtz-hiri.de www.imib-wuerzburg.de/research/vogel/research Project description: The HIRI is recruiting a postdoctoral researcher to develop new types of RNA-seq approaches that are capable of profiling gene expression changes and post-transcriptional control in single bacteria. The ultimate goal of this project is to achieve a high-resolution of heterogeneity in bacterial infection samples. For other research themes in the Vogel lab and more information on methodology, see some of our recent publications (Westermann AJ et al. 2016 Dual RNA-seq unveils noncoding RNA functions in host-pathogen interactions. Nature 529:496-501; Smirnov A et al. 2016 Grad-seq guides the discovery of ProQ as a major small RNA binding protein. PNAS 113:11591-6; Saliba AE et al. 2017 Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella. Nature Microbiology 2:16206). The successful applicant will work in the dynamic environment of the Vogel lab at the HIRI in Würzburg.
- PhD or equivalent in bioinformatics, microbiology, genomics, computer science, engineering, data science, or a related field
- Previous experience with RNA-seq would be desirable
- Ability to work independently and as part of an international team
- A strong desire to do research
- Enthusiasm, creativity, and strong self-motivation
- Excellent English communication skills (written and spoken)
The HIRI expressly invites women to apply. Equally well-qualified disabled applicants will be given preference. Part time is possible upon request.
- RNA Biologie bakterieller Infektionen - Prof. Jörg Vogel
Initial term 3 years
E 13/14 TVöD/Bund
Bewerbungsschluss ist der 09.01.2019
Applications should include a short cover letter, CV without a picture, publication list, copies of relevant documents and contact information for academic references as a single PDF file stating the job announcement 81/2018 via email to JobsHZI@helmholtz-hzi.de.
For informal inquiries, please contact Prof. Jörg Vogel (firstname.lastname@example.org).
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Die HZI International Graduate School for Infection Research (GS-FIRE) bietet ein innovatives, strukturiertes Promotionsprogramm im Themenbereich "Infektionsforschung".