Postdoctoral position: “Countering CRISPR-based gene drives” (f, m, d)

Kennziffer: Job announcement No. 74/2019



The Helmholtz Institute for RNA-based Infection Research (HIRI) is offering a Postdoctoral position: “Countering CRISPR-based gene drives” (f, m, d) in the Research Group of RNA Synthetic Biology (RSYN) under the direction of Prof. Chase Beisel. The Helmholtz Institute for RNA-based Infection Research (HIRI) was established in May 2017 as a joint venture between the Helmholtz Centre for Infection Research (HZI) in Braunschweig and the Julius Maximilian University of Würzburg (JMU). The HIRI is the first research institution worldwide to exclusively address the role of ribonucleic acids (RNA) in infection processes. Based on novel findings, innovative therapeutic approaches are developed in an integrated research approach and made clinically usable through the development of pharmaceutical forms of application. For more information, please visit


The RSYN research group focuses on characterizing and harnessing CRISPR-Cas systems toward better understanding, diagnosing, and treating human infections. The postdoc will participate on an active DARPA project developing countermeasures against CRISPR-based gene drives. The project involves developing various RNA-based countermeasure strategies to inhibit CRISPR nucleases and validating these strategies in cell-free systems, bacteria, and yeast. The project also involves a close collaboration implementing these strategies in mosquitos.



Your profile/qualifications:

  • PhD or equivalent in biology, microbiology, genomics, engineering, or a related field
  • Highly motivated and independent
  • Strong written and spoken English language communication skills 

Desired (non-essential) background:

  • Previous experience in synthetic biology, yeast genetics, CRISPR technologies, and/or RNA design
  • Familiar with advanced cloning techniques (e.g. Golden Gate assembly, Gibson assembly)

Our range/offer:

We offer compensation according to TVöD and varied activities on an international team. The hiring is through the Helmholtz Center for Infection Research GmbH in Braunschweig. The place of employment is Würzburg. Disabled applicants will be preferred, given they possess equal professional qualifications. Equal opportunities are part of our personnel policy – qualified women are especially invited to apply. The position is suitable for a part-time employment.

Starting date: As early as October 1, 2019. Initial funding ends May, 2021, although  longer-term funding will be sought.

Remuneration: E 14 TVöD / Bund

Workplace: Würzburg

Probation: 6 months

Application deadline: 1 September, 2019


HIRI Würzburg



As early as October 1


Initial funding ends May, 2021, although longer-term funding will be sought.


6 months


E 14 TVöD / Bund



Bewerbungsschluss ist der  01.09.2019

We look forward to receiving your detailed application (Cover letter, CV without picture, and certificates) quoting the reference number 74/2019, summarized in a single pdf document, preferably by e-mail to or to:
Helmholtz Center for Infection Research GmbH, Personnel department, Inhoffenstraße 7,38124 Braunschweig

For questions please contact Prof. Dr. Chase Beisel via e-mail at the following address:

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