16.11.2016
Kennziffer
44/2016

2 PhD candidates for the ERC project SWEETBULLETS

CBCH

Dr. Titz was awarded an ERC Starting Grant for the development of future drugs and analytical tools against such bacterial infections. The group is now recruiting 2 PhD candidates for the ERC project SWEETBULLETS, with the main focus on Design and Multistep Organic Synthesis of novel antiinfectives.

Aufgabenbereich

The Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) was founded by the Helmholtz Centre for Infection Research (HZI) Braunschweig and Saarland University in summer 2009. It is the aim of HIPS to develop new pharmaceuticals and therapies against infectious diseases.

The combination of expertise in infection research and pharmaceutical sciences at HZI and HIPS is a unique setting in Germany and Europe, especially in the development of new antiinfectives. Since October 2015, the institute is located in a brand new state-of-the-art research building on the university campus in Saarbrücken, the capital of Saarland.

The Helmholtz Young Investigator Group "Chemical Biology of Carbohydrates", headed by Dr. Alexander Titz, studies the role of carbohydrates in disease with a focus on lectins in chronic Pseudomonas aeruginosa infections. In his interdisciplinary group, a variety of methods are used to analyse the role of these carbohydrate-binding proteinaceous subunits of the biofilm architecture: organic synthesis of inhibitors, biochemistry and biophysics, molecular biology and microbiology. The group is part of the German Centre for Infection Research (DZIF) which is dedicated to the translation of research into clinical applications.

Project

  • Main Focus: Design and Multistep Organic Synthesis of novel antiinfectives
  • Biochemical/biological evaluation of synthesized compounds

Our offer 

  • Cutting edge research project
  • State-of-the-art lab infrastructure
  • Young and international group

Voraussetzungen

  • MSc degree or equivalent in Chemistry or related disciplines
  • Strong focus on Synthetic Organic Chemistry
  • Open-minded and curious personality
  • Highly motivated and self-driven

Standort

HIPS Saarbrücken

Forschungsgruppe

Schwerbehinderte

Bei gleicher fachlicher Eignung erhalten Schwerbehinderte den Vorzug.

Einstellungstermin

Early 2017

Befristung

Initial term for one year, with the possibility of an extension for additional two years

Probezeit

6 months

Vergütung

55% EG 13 (TVöD Bund)

Veröffentlicht

16.11.2016

Applications should contain a cover letter stating your particular interest, your CV, copies of diplomas and GPA or equivalent, and the contact details of 2 references. Please send all assembled into one single PDF file (max. 5 MB) to Dr. Alexander Titz, per email: alexander.titz@helmholtz-hzi.de.

Further information and current publications of Dr. Titz’s group can be found here: http://www.helmholtz-hzi.de/cbch.