Neurophysiology/structural biology/microbiology PhD project

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Neurophysiology/structural biology/microbiology PhD project: Bacterial infections targeting synaptic adhesion molecules: effects of bacterial adhesin binding to adhesive components of photoreceptor/retinal synapses

We are looking to recruit a highly motivated PhD student for a joint research project between the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS, Saarbrücken, Germany - a branch of the Helmholtz Centre for Infection Research) and Saarland Medical University (UKS, Homburg, Germany).

The project on bacterial adhesins binding to neuronal structures is highly interdisciplinary and ranges from molecular microbiology/structural biology to neurophysiology and will include bacterial and mammalian protein expression, crystallization studies, synaptic physiology using genetically engineered reporter mice, Ca2+ imaging, cell wall associated proteome studies, and different adhesion assays including single molecule force spectroscopy.

Further information on the three research groups of

Prof. Dr. Schmitz (

Prof. Dr. Köhnke (, and

Prof. Dr. Bischoff (

can be found online.


The ideal candidate has a MSc degree in Biology (or related) with previous MSc thesis research expertise in neurophysiology, structure biology, and/or microbiology. Willingness to routinely work under biosafety level S2 and with mice is essential.

Related Subjects

  • Medical / Clinical Science
  • Neurophysiology
  • Structural Biology
  • Microbiology
  • Molecular Biology


HIPS Saarbrücken



The desired starting date is between 11/2019 and 02/2020.



Bewerbungsschluss ist der  30.09.2019

Applications are only accepted electronically as a single PDF file containing the relevant information (motivation letter, CV, A-level/BSc/MSc diplomas, transcripts of records, names of 2 references, and, if available, letters of recommendation). Please send them to all three email addresses ( and in parallel.

Applications will be continuously reviewed until the position has been filled.

Wussten Sie schon?

HZI International Graduate School for Infection Research

Die HZI International Graduate School for Infection Research (GS-FIRE) bietet ein innovatives, strukturiertes Promotionsprogramm im Themenbereich "Infektionsforschung".

PHD-Studiengang Epidemiologie

Der PhD-Studiengang „Epidemiologie“ ist ein dreijähriger Promotionsstudiengang im Bereich der epidemiologischen Forschung und wird von der Abteilung für Epidemiologie des HZI betrieben.

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