Transgene Mäuse

Brown, R.J.P., Tegtmeyer, B., Sheldon, J., Khera, T., Anggakusuma, Todt,D., Vieyres, G., Weller, R., Joecks, S., Zhang, Y.,Sake, S., Bankwitz, D., Welsch, K., Ginkel, C., Engelmann, M., Gerold, G., Steinmann, E.,Yuan, Q., Ott, M., Vondran, F.W.R., Krey, T., Stroh, L.J.,Miskey, C., Ivics, Z., Herder, V., Baumgartner, W., Lauber, C., Seifert, M., Tarr, A.W., McClure, C.P., Randall, G., Baktash, Y., Ploss, A., Thi, V.L.D., Michailidis, E., Saeed, M., Verhoye, L., Meuleman, P., Goedecke, N., Wirth, D., Rice, C.M., Pietschmann, T. (2020) Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. Sci Adv 6: eabd3233. 
DOI: 10.1126/sciadv.abd3233.

Ziegler, P.K., Bollrath, J., Pallangyo, C.K., Matsutani, T., Canli, Ö., De Oliveira, T., Diamanti, M.A., Müller, N., Gamrekelashvili, J., Putoczki, T., Horst, D., Mankan, A.K., Öner, M.G., Müller, S., Müller-Höcker, J., Kirchner, T., Slotta-Huspenina, J., Taketo, M.M., Reinheckel, T., Dröse, S., Larner, A.C., Wels, W.S., Ernst, M., Greten, T.F., Arkan, M.C., Korn, T., Wirth, D., Greten, F.R. (2018) Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis. Cell 174: 88-101.
DOI: 10.1016/j.cell.2018.05.028.

Gödecke, N., Zha, L., Spencer, S., Behme, S., Riemer, P., Rehli, M., Hauser, H., Wirth, D. (2017) Controlled re-activation of epigenetically silenced Tet promoter-driven transgene expression by targeted demethylation. Nucl Acids Res,
DOI:10.1093/nar/gkx601. 

Cebula, M., Riehn, M., Hillebrand, U., Kratzer, Ramona, Kreppel, F., Koutsoumpli, G., Daemen, T., Hauser, H., Wirth, D. (2017) TLR9 mediated conditioning of the liver environment is essential for successful intrahepatic immunotherapy and effective memory recall. Molecular Therapy 25 (10): 2289-2298.
DOI: 10.1016/j.ymthe.2017.06.018

Haenebalcke L., Goossens S., Dierickx P., Bartunkova S., D'Hont J., Haigh K., Hochepied T., Wirth D., Nagy A., Haigh J.J .(2013) The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)differentiation. Cell reports 3: 335-341.
DOI:10.1016/j.celrep.2013.01.016

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