Modellsysteme für Infektion und Immunität

Kumashie, K.G., Cebula, M., Hagedorn, C., Kreppel, F., Pils, M.C., Koch-Nolte, F., Rissiek, B., and Wirth, D. (2021). Improved Functionality of Exhausted Intrahepatic CXCR5+ CD8+ T Cells Contributes to Chronic Antigen Clearance Upon Immunomodulation. Front Immunol 11, 592328.
DOI: 10.3389/fimmu.2020.592328

Gödecke, N., Riedel, J., Herrmann, S., Behme, S., Rand, U., Kubsch, T., Cicin-Sain, L., Hauser, H., Köster, M., Wirth, D. (2020) Synthetic rewiring and boosting type I interferon responses for visualization and counteracting viral infections. Nucl Acids Res 48: 11799-11811.
DOI: 10.1093/nar/gkaa961

Ullah, S., Seidel, K., Turkkan, S., Warwas, D.P., Dubich, T., Rohde, M., Hauser, H., Behrens, P., Kirschning, A., Köster, M., Wirth, D.(2019) Macrophage entrapped silica coated superparamagnetic iron oxide particles for controlled drug release in a 3D cancer model.      J Control Release 294:327-336.
DOI: 10.1016/j.jconrel.2018.12.040

Cebula, M., Riehn, M., Hillebrand, U., Kratzer, Ramona, Kreppel, F., Koutsoumpli, G., Daemen, T., Hauser, H., Wirth, D. (2017) TLR9 mediated conditioning of the liver environment is essential for successful intrahepatic immunotherapy and effective memory recall. Molecular Therapy 25 (10): 2289-2298.
DOI:10.1016/j.ymthe.2017.06.018

Gödecke, N., Zha, L., Spencer, S., Behme, S., Riemer, P., Rehli, M., Hauser, H., Wirth, D. (2017) Controlled re-activation of epigenetically silenced Tet promoter-driven transgene expression by targeted demethylation. Nucl Acids Res Sep 19;45(16):e147
DOI:10.1093/nar/gkx601 

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