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Host genetic susceptibility to Mycobacterium tuberculosis
This project is funded by the Presidential Fund of the Helmholtz-Association.
Coordinator: Prof. Dr. Klaus Schughart
In the context of the Helmholtz-Russian Joint Research Group (HRJRG), we work together with the laboratory of Alexander Apt at the Tuberculosis Centre in Moscow on the genetic susceptibility to Mycobacterium tuberculosis infections in the mouse model. The gene expression changes in susceptible and resistant mouse strains after infection with M. tuberculosis in the lung will be studied in our laboratory, the genetics of inbred and congenic resistant and susceptible mouse strains will be analyzed by the laboratory in Moscow.