Hans-Curt Flemming „How biofilms organize their life – the role of the EPS matrix“


  • Überblick


    Biofilms are the oldest and most abundant form of life on Earth. In biofilms, microorganisms live in their self-produced matrix of hydrated extracellular polymeric substances (EPS), which determine the immediate environment and the conditions of life for biofilm organisms. EPS are mainly polysaccharides, proteins, nucleic acids and lipids. They provide the mechanical stability of biofilms, mediate their adhesion to surfaces and provide a cohesive, three-dimensional polymer network interconnecting and immobilizing biofilm cells. This leads to the development of microbial communities of high cell density, allowing for intense cell-cell communication and orchestrating metabolic performance. The biofilm matrix acts as an external digestion system, keeping extracellular enzymes close to biofilm cells, capable of metabolising dissolved, colloidal and solid biopolymers. Due to the physiological activity of biofilm organisms, gradients develop, creating different habitats which support high biodiversity. The EPS matrix is a key to understand the biofilm mode of life.


    Hans-Curt Flemming was born 1947 at the Lake Constance, between Germany, Switzerland and Austria. He studied Chemistry in Freiburg and Stuttgart and did his Ph. D. at the Max Planck Institute for Immunology in Freiburg on the biosynthesis of bacterial exopolysaccharides. At the University of Stuttgart, he implemented the Biofilm Research group between 1986 and 1994, when he went to the University of Munich to establish the Biotechnology group. In 1996 he got a position as chair for Aquatic Microbiology at the University of Duisburg-Essen. He also is a member of the Board of Directors of the IWW Water Centre in Mülheim. In 2000, he was one of the founders of the interdisciplinary curriculum “Water Science” which includes chemistry, analytics and microbiology of water. His main research focus is microbial biofilms. Since 2012, he is a visiting professor at the Nanyang Technical University of Singapore, active in the Singapore Center for Life Science Engineering. He has published about 300 scientific papers and 10 books. Currently, he is the chairman of the BioCluster, a joint activity of the International Water Association (IWA) and the International Society of Microbial Ecology (ISME).

    Datum: 03.09.2013, 17:00


    Universität des Saarlandes

    Gebäude und Raum

    Raum 02 in Gebäude B2.1


    Hans-Curt Flemming,
    Universität Düsseldorf


    Rolf W. Hartmann

  • Anfahrt

    So erreichen Sie uns in Saarbrücken

    Das HIPS-Gebäude befindet sich am Osteingang des Saarbrücker Campuses der Universität des Saarlandes. Der Campus liegt vor den Toren der Innenstadt in einem Waldgebiet. Saarbrücken ist die Hauptstadt des Saarlandes, welches im Südwesten Deutschlands liegt und gemeinsame Grenzen mit Frankreich und Luxemburg besitzt.


    Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS)
    Universitätscampus E8 1
    66123 Saarbrücken

    Mit dem Auto

    • von Norden (Köln/Trier) über die Autobahnen A1/A8 zum Autobahnkreuz Neunkirchen, dort A6 in Richtung Saarbrücken
    • von Osten (Kaiserslautern) über die A6
    • von Nord-Westen (Luxemburg) über die A620, vorbei am Stadtzentrum auf die A6 in Richtung Mannheim
    • von Westen (Paris/Metz) und Süden (Strasbourg) über die A6/E50 in Richtung Mannheim

    Ausfahrt Nr. 6, "St. Ingbert-West/Universität" der Beschilderung "Universität Ost" folgen (ca. 6 km)

    Mit dem Zug

    • ICE/TGV- und Intercity-Bahnhof Saarbrücken Hbf
    • man kann den Campus mit Öffentlichen Verkehrsmitteln vom Hauptbahnhof (Linien 112, 124) und aus dem Stadtzentrum (Linien 101, 102, 109, 111) innerhalb von ca. 15 min. erreichen



  • Birgitta Lelarge

    Birgitta Lelarge

    Assistentin der Geschäftsführung

    0681 98806-3022

    0681 98806-3003