Research Projects

  • ALERTS-NET: Incidence of nosocomial blood stream infections, antibiotic resistances and blood culture ordering and testing practices – a Thuringia-wide prospective population-based surveillance cohort study
  • ANTI-INFEKTIVA: Analysis of the mechanisms of action of anti-infectives
  • AQUAVALENS : Protecting the health of Europeans by improving methods for the detection of pathogens in drinking water and water used in food preparation.
  • TREATMENT : Drug-loaded nano- and microparticles for the treatment of inflammatory bowel diseases
  • BIBA: Delivering nanopharmaceuticals through Biological Barriers
  • BIOFILM-INHIBITOREN_MINS: Development of inhibitors for prevention and treatment of biofilms caused by pathogenic bacteria
  • CERVICO-VAGINAL SELF-SAMPLING AND PATHOGEN DETERMINATION: Cervico-vaginal self-sampling and pathogen determination
  • CHAGAS DISEASE: Development and testing of prophylactic and therapeutic vaccine candidates against Chagas disease
  • CILIA: Konditionale Immortalisierung alveolarer Epithelzellen zur Etablierung infektionsrelevanter in vitro Modelle der Lunge/ Conditional Immortalization of Alveolar Epithelial Cells
  • COMBACTE : Combating Bacterial Resistance in Europe
  • COMPACT: imi – Innovative Medicines Initiative: Collaboration on the Optimisation of Macromolecular Pharmaceutical Access to Cellular Targets
  • COMPARISON OF STOOL SAMPLING AT HOME VERSUS AT THE STUDY CENTER: Comparison of stool sampling at home versus at the study center
  • CYTOMEGALOVIRUS: Molecular mechanisms of persistent antigenic stimulation in cytomegalovirus infection
  • LAB – IN – A – HANKIE : New tools for the diagnosis of Candida albicans
  • DIABETIC FOOT INFECTIONS: Metagenomics and host-pathogen interactomics in diabetic foot infections
  • DIS-Z-KONJUGATE : Disorazol-Z-Konjugate zur zielgerichteten, rezeptorabhängigen Therapie solider Tumore
  • DZIF: GASTROINTESTINAL INFECTIONS: TTU 06.801: Identification of novel inhibitors targeting coloisation and virulence of gastrointestinal pathogens
  • EATRIS: The European Advanced Transnational Research InfraStructure in Medicine
  • EMTRAIN: European Medicines Research Training Network
  • EU-OPENSCREEN: European Infrastructure of Open Screening Platforms for Chemical Biology
  • EXPRESSYS: Expression and high-througput screening of myxobaterial enzymes
  • FBI-ZOO: TP10: Serotype and host specific colonisation of enteropathogenic Yersinia and its persistence in the host and in food
  • FIDEL: KMU-innovativ-Verbundprojekt: Nanopartikuläres Drug Delivery System zur Behandlung chronischer Pseudomonas Aeruginosa Infektionen bei Cystischer Fibrose
  • FLURESEARCHNET: Molecular signatures determining pathogenicity and species transmission of influenza A viruses
  • GERMAN-EGYPTIAN RESEARCH PROJECT: Mutation detection and molecular genetic diagnosis of the Egyptian H1N1 and H5N1 viral strains
  • GERONTOSHIELD: Systems biology-driven approach to unravel and revert the mechanisms responsible for poor immune responses in the elderly
  • HCVAX: Novel vaccines against Hepatitis C using nanotechnology
  • HEPTROMIC: Genomic predictors and oncogenic drivers in hepatocellular carcinoma
  • HIS MICE: Improving predictability of preclinical data
  • IG-SCID: Indo-German Science Center for Infectious Diseases - Gemeinsam gegen Infektionskrankheiten
  • VACCINATION: Needle-free transdermal vaccination
  • IN VITRO MODEL: Development of a new in vitro model of the air-blood-barrier
  • INFECT: Systems medicine to understand severe soft tissue infections
  • INFRAFRONTIER: The European infrastructure for phenotyping and archiving of model mammalian genomes
  • INFRAFRONTIER: Infection challenge - Secondary phenotyping of mouse mutant lines
  • KFO 250: Genetische und zelluläre Mechanismen von Autoimmunerkrankungen
  • LEGIONELLA POPULATIONS IN FRESHWATER SYSTEMS IN GERMANY, PALESTINE AND ISRAEL: Understanding the ecology and virulence of Legionella spp. populations in freshwater systems in Germany, Palestine and Israel
  • MAGICPAH: Molecular Approaches and MetaGenomic Investigations for optimizing Clean-up of PAH contaminated site
  • MAST CELLS: Phagocytosis-independent antimicrobial activity of mast cells by formation of extracellular traps: cellular receptors involved and underlying molecular mechanism
  • MATHEMATICAL MODELING OF THE EFFECTS OF VARICELLA VACCINATION IN GERMANY: Mathematical modeling of the effects of varicella vaccination in Germany
  • METABOLIC DYSFUNCTION: Metabolic Dysfunction and Human Diseases
  • MINAS MICROBIAL NATURAL PRODUCTS: Novel screens and novel compounds - fighting biofilms with myxobacterial and fungal metabolites
  • MUSE: Gastrointestinal Erreger (Serum und Stuhl)
  • MYCOBACTERIUM TUBERCULOSIS: Novel targets for short-course tuberculosis therapy
  • MCMV-INFECTION: IFN-mediated control of chronic CMV infection
  • NATIONAL COHORT: National Cohort
  • OPTISTEM: Optimization of Stem cell Therapy for degenerative Epithelial and Muscle Diseases
  • PETRA: Platforms for the efficient epithelial transport of pharmaceutical applications using innovative particulate transport systems
  • PQS QUORUM SENSING COMMUNICATION SYSTEM: Development of molecules that interfere with the PQS quorum sensing communication system in Pseudomonas aeruginosa
  • PROTRAIN TPO3: Atomic structures and reaction mechanisms of proteins involved in transfer and insertion of molybdenum cofactor and heme
  • QUESTIONNAIRE TO SCREEN FOR SELECTED INFECTIOUS DISEASES IN POPULATION-BASED EPIDEMIOLOGICAL STUDIES: Questionnaire to screen for selected infectious diseases in population-based epidemiological studies
  • RNAP: Development of potent inhibitors of the bacterial RNA polymerase for the treatment of infections with Mycobacterium tuberculosis
  • S-SWAB: Methicillin-resistant and –sensitive Staphylococcus aureus carriage in the general population – transmission, risk factors and associated infections
  • S. AUREUS: Identifizierung genetischer Faktoren und immunologischer Mechanismen welche der Resistenz oder Suszeptibilität gegenüber S. aureus in Mausmodellen zugrunde liegen
  • SFB 51 - ROSEOBACTER: Ecology, Physiology and Molecular Biology of the Roseobacter clade: Towards a Systems Biology Understanding of a Globally Important Clade of Marine Bacteria
  • SFB 587: Immunreactions of the Lung in Infection and Allergies
  • SFB 587: TEILPROJEKT B12: Untersuchungen zur Immunregulation bei akuter und chronischer CD4+ T-Zell-vermittelter Erkrankung der Lunge
  • SFB 599: Sustainable bioresorbable and permanent implants of metallic and ceramic materials.
  • SFB 621: Pathobiology of the Intestinal Mucosa
  • SFB 738: Optimisation of Conventional and Innovative Transplants
  • SFB 854: Molecular Organisation of Cellular Communication in the Immune System
  • SFB 900: Chronische Infektionen: Mikrobielle Persistenz und ihre Kontrolle
  • SPP 1258: Sensory and regulatory RNAs in Prokaryotes
  • SPP 1316: Host-Adapted Metabolism of Bacterial Pathogens
  • SPP 1394: Mast-cells - promoters of health and modulators of disease
  • SPP 1617: Projekt: Underlying principles of bistability in the expression of the pivotal virulence regulator RovA in Yersinia pseudotuberculosis and role for virulence
  • SUCHE NACH NEUEN NATURSTOFFEN: DFG FOR 1406 TP1: Suche nach neuen Naturstoffen basierend auf bakterieller Biodiversität, Bioaktivität-Screenings und moderner analytischer Chemie
  • SYSGENET: COST Action BM0901 - European systems genetics network for the study of complex genetic human diseases using mouse genetic reference populations
  • TRANSPLANTATION COHORT: Establishment of a novel prospective and observational national transplantation cohort
  • DELIVERY CARRIERS: Design of new gene delivery carriers
  • TRANSVAC: European Network of Vaccine Research and Development
  • TUBULYSIN DERIVATE: DFG FOR 1406 TP2: (Bio)Synthese von Tubulysin Derivaten für biologische und Biosynthese-Studien
  • USE OF WEB-BASED TOOLS TO COLLECT DATA ON INFECTIOUS DISEASES IN POPULATION-BASED EPIDEMIOLOGICAL STUDIES: Use of web-based tools to collect data on infectious diseases in population-based epidemiological studies
  • VACCINATION RECORD RETRIEVAL: Vaccination record retrieval
  • VISTRIE: Viral Strategies of Immune Evasion
  • DRUG RESEARCH: Helmholtz Drug Research Initiative

More Information

Completed Research Projects

An overview of our completed Research Projects can be found here:

Finished Research Projects