Helmholtz-Zentrum für Infektionsforschung

Helmholtz-Zentrum für Infektionsforschung

Structural biology of autophagy (autophagocytosis)

Cells continuously synthesize proteins, reconstruct their organelles and cellular components, renew them and take up substances from outside. A cellular mechanism that counteracts and controls this on-going growth of organic matter is autophagy. This particular mechanism degrades everything that is no longer needed – and this includes pathogens as well. In this regard autophagy plays a central role in our immune response and the defence against infectious diseases. Here you can find out how our scientists are researching autophagy in order to fight against pathogens and infectious diseases.

Head of Research Group

Dr. Andrea Scrima

“Once we are able to understand the structure of central elements within autophagy and the camouflage-mechanisms of pathogens, we can identify new antibacterial substances that can inhibit this “camouflage.”

More about our research

Our Research

How does the cell regulate the degradation mechanism autophagy? How do pathogens exploit autophagy for their own benefit? And how can we use these processes to counteract and manipulate pathogen-mediated infections?

Members of Staff

Team list

Contact Data

Contact data of all members of the research group.

Scientific Publications

Publications

Results and Publications of our research activities.




Publications Search

Publications Search

Contact

Head of the Research Group:
Dr. Andrea Scrima

Tel. +49 531 6181-7013

Infection-Research Worldwide

Highlights of infection research at a glance more





24.05.2012