The focus of our work is the study and investigation of pathogens which are medically relevant or can be used as models for researching infection mechanisms.
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Around 700 employees in research, administration and infrastructure, and about 140 visiting scientists from 40 different countries are employed at the Helmholtz Centre for Infection Research.
Our scientists pursue research to expand our knowledge of the fundamental mechanisms behind medically relevant infectious diseases.
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How do bacteria, viruses, parasites and fungi make us sick? How does our immune system defend our body?
These are the questions we at the HZI want to answer. Our goal: To set up the basis for new diagnostic tools, new active agents and new therapies against infectious diseases.
21.11.2012, 17:15 - HZI-Kolloquium - Scientific
The ubiquitin-proteasome-system (UPS) is responsible for the maintenance of cellular protein homeostasis. Upon an infectious challenge and/or the release of interferons standard proteasomes are replaced by newly synthesized immunoproteasome complexes. Recent data indicate that immunoproteasomes have important immunological functions beyond MHC class I antigen processing. In addition, the role of the UPS in two different infection models will be discussed.
Helmholtz Centre for Infection ResearchInhoffenstraße 738124 Braunschweig+49 531 firstname.lastname@example.org
Helmholtz Institute for Pharmaceutical Research SaarlandCampus, Geb. C2.3Universität des Saarlandes66123 Saarbrücken+49 681 email@example.com
TWINCOREZentrum für Experimentelle und Klinische InfektionsforschungFeodor-Lynen-Str. 730625 Hannover+49 511 firstname.lastname@example.org
Study Centre HannoverFeodor-Lynen-Straße 530625 Hannover+49 511 email@example.com