Manuel Buttini "Neuroinflammation: Friend or Foe?"

Inflammation is a defence reaction against insults or infections, designed to remove noxious agents and to inhibit their detrimental effects. Inflammation accompanies all neurological afflictions, such as traumatic brain injuries, nervous system infections, and chronic neurodegenerative diseases such as Alzheimer’s or Parkinson’s diseases. Neuroinflammation, while having a number of specific features, is at least as intricate and tightly regulated as its counterpart in the periphery. It can be triggered by the accumulation of abnormal proteins, by signals emanating from injured neurons, or by infectious agents invading nervous tissue. Inflammatory processes can either promote or counteract neurodegenerative processes, and it has been difficult to pinpoint their roles in specific pathological situations. Many insights about the role of different inflammatory factors and cellular mediators in the nervous system have come over the last decade from animal model studies. The seminar will give an overview on what these studies have revealed about the role of inflammation in the nervous system. One overall theme that will emerge is that, since many inflammatory responses are beneficial, directing and instructing the inflammatory machinery may be a better therapeutic objective than just suppressing it.

• Overview

  The "HZI Colloquium" is a scientific lecture series at the Helmholtz Centre for Infection Research in Braunschweig, organized to host internationally renowned experts from the field of infection research. Invited guest speakers present their current research activities to a scientific audience. The presentation is followed by an open discussion.
  We cordially invite interested scientists to take part in this colloquium.
  The HZI Colloquium takes place on Wednesdays, 5.15 p.m. to 6.30 p.m. in the Forum, X0.13.

  
  

  Date: 28.11.2012, 17:15

  Location

  Helmholtz Centre for Infection Research

  Building and room

  Forum, X0.13
  
  

  Speaker

  Manuel Buttini,
  Luxembourg Centre for Systems Biomedicine, Université de Luxembourg

  Host

  Klaus Schughart

• Directions

  How to find us in Braunschweig

  

  Address

  Helmholtz Centre for Infection Research

  Inhoffenstraße 7

  38124 Braunschweig

  Car

  From Berlin/Wolfsburg/Helmstedt:

  • A2 till motorway interchange Wolfsburg/Königslutter > A39 direction Kreuz BS-Süd/Wolfenbüttel/Bad Harzburg
  • A39 till motorway interchange Kreuz BS Süd > A395 direction Wolfenbüttel
  • A395 till exit BS-Stöckheim > turn right into Mascheroder Weg
  • after 500m turn left into Inhoffenstraße

  From Celle/Hannover:

  • A2 till motorway interchange Kreuz BS Nord > A391 direction Kreuz BS Süd/Bad Harzburg/Wolfenbüttel
  • A391 motorway interchange Kreuz BS Süd > A395 direction Wolfenbüttel
  • A395 till exit BS-Stöckheim > turn right into Mascheroder Weg
  • after 500m turn left into Inhoffenstraße

  From Kassel/Salzgitter:

  • A7 till motorway interchange Kreuz Salzgitter > A39 direction Berlin/Braunschweig/Salzgitter
  • A39 till motorway interchange Kreuz BS-Süd > A395 direction Wolfenbüttel
  • A395 till exit BS-Stöckheim > turn right into Mascheroder Weg
  • after 500m turn left into Inhoffenstraße

  Train

  

  Braunschweig Central Station has got two Intercity-Express-Lines, which are connecting Berlin-Braunschweig-Göttingen-Fulda-Frankfurt-Mannheim. 

  Two other Intercity-Lines are in direction to Leipzig, Halle, Magdeburg and Hannover, Bremen, Oldenburg, Bielefeld, Wuppertal and Köln.

  Here you'll get more information about the timetable.

  Bus or Tram

  Bus line 431 or Tram line 1 from central station to stop "Stöckheimer Markt". Turn left into "Mascheroder Weg" and after 500m turn right into "Inhoffenstraße". 

  Futher links:

  Braunschweig traffic corporation
  

  Electronic time table (EFA)

  Map provided by the city of Braunschweig

  Airplane

  Hannover Airport is about 60 minutes away from Braunschweig (60km). You can hourly take a train in direction of Braunschweig.

  From the International Airport Frankfurt you can reach Braunschweig in 180 minutes by train and it's about 350km away.

  Berlin's Airports Schönefeld and Tegel are 120 minutes away from Braunschweig (230km). A train in direction of Braunschweig leaves every hour.

  
  

  Downloads

  • Travelling by car (jpg, 497 kb)
  • Gelaendeplan HZI (pdf, 3.4 mb)

Contact

• Prof. Dr. Klaus Schughart

  

  Head of Department Infection Genetics

  +49 531 6181-1100

  +49 531 6181-1199

  Contact

  CV and Publications

• Dr. Sonja Horatzek

  

  Internal communication / Online communication

  +49 531 6181-1403

  +49 531 6181-1499

  Contact

Involved Groups

• Infection Genetics - Prof. Dr. Klaus Schughart