Manuel Buttini "Neuroinflammation: Friend or Foe?"

Buttini

Inflammation is a defence reaction against insults or infections, designed to remove noxious agents and to inhibit their detrimental effects. Inflammation accompanies all neurological afflictions, such as traumatic brain injuries, nervous system infections, and chronic neurodegenerative diseases such as Alzheimer’s or Parkinson’s diseases. Neuroinflammation, while having a number of specific features, is at least as intricate and tightly regulated as its counterpart in the periphery. It can be triggered by the accumulation of abnormal proteins, by signals emanating from injured neurons, or by infectious agents invading nervous tissue. Inflammatory processes can either promote or counteract neurodegenerative processes, and it has been difficult to pinpoint their roles in specific pathological situations. Many insights about the role of different inflammatory factors and cellular mediators in the nervous system have come over the last decade from animal model studies. The seminar will give an overview on what these studies have revealed about the role of inflammation in the nervous system. One overall theme that will emerge is that, since many inflammatory responses are beneficial, directing and instructing the inflammatory machinery may be a better therapeutic objective than just suppressing it.

  • Overview

    The "HZI Colloquium" is a scientific lecture series at the Helmholtz Centre for Infection Research in Braunschweig, organized to host internationally renowned experts from the field of infection research. Invited guest speakers present their current research activities to a scientific audience. The presentation is followed by an open discussion.
    We cordially invite interested scientists to take part in this colloquium.
    The HZI Colloquium takes place on Wednesdays, 5.15 p.m. to 6.30 p.m. in the Forum, X0.13.


    Date: 28.11.2012, 17:15

    Location

    Helmholtz Centre for Infection Research

    Building and room

    Forum, X0.13

    Speaker

    Manuel Buttini,
    Luxembourg Centre for Systems Biomedicine, Université de Luxembourg

    Host

    Klaus Schughart

  • Directions

    How to find us in Braunschweig

    Lage des Helmholtz-Zentrums in der Stadt Braunschweig.

    Address

    Helmholtz Centre for Infection Research

    Inhoffenstraße 7

    38124 Braunschweig

    Car

    From Berlin/Wolfsburg/Helmstedt:

    • A2 till motorway interchange Wolfsburg/Königslutter > A39 direction Kreuz BS-Süd/Wolfenbüttel/Bad Harzburg
    • A39 till motorway interchange Kreuz BS Süd > A395 direction Wolfenbüttel
    • A395 till exit BS-Stöckheim > turn right into Mascheroder Weg
    • after 500m turn left into Inhoffenstraße

    From Celle/Hannover:

    • A2 till motorway interchange Kreuz BS Nord > A391 direction Kreuz BS Süd/Bad Harzburg/Wolfenbüttel
    • A391 motorway interchange Kreuz BS Süd > A395 direction Wolfenbüttel
    • A395 till exit BS-Stöckheim > turn right into Mascheroder Weg
    • after 500m turn left into Inhoffenstraße

    From Kassel/Salzgitter:

    • A7 till motorway interchange Kreuz Salzgitter > A39 direction Berlin/Braunschweig/Salzgitter
    • A39 till motorway interchange Kreuz BS-Süd > A395 direction Wolfenbüttel
    • A395 till exit BS-Stöckheim > turn right into Mascheroder Weg
    • after 500m turn left into Inhoffenstraße

    Train

    Braunschweig Central Station has got two Intercity-Express-Lines, which are connecting Berlin-Braunschweig-Göttingen-Fulda-Frankfurt-Mannheim. 

    Two other Intercity-Lines are in direction to Leipzig, Halle, Magdeburg and Hannover, Bremen, Oldenburg, Bielefeld, Wuppertal and Köln.

    Here you'll get more information about the timetable.

    Bus or Tram

    Bus line 431 or Tram line 1 from central station to stop "Stöckheimer Markt". Turn left into "Mascheroder Weg" and after 500m turn right into "Inhoffenstraße". 

    Futher links:

    Braunschweig traffic corporation

    Electronic time table (EFA)

    Map provided by the city of Braunschweig

    Airplane

    Hannover Airport is about 60 minutes away from Braunschweig (60km). You can hourly take a train in direction of Braunschweig.

    From the International Airport Frankfurt you can reach Braunschweig in 180 minutes by train and it's about 350km away.

    Berlin's Airports Schönefeld and Tegel are 120 minutes away from Braunschweig (230km). A train in direction of Braunschweig leaves every hour.


    Downloads

Contact

Involved Groups