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The focus of our work is the study and investigation of pathogens which are medically relevant or can be used as models for researching infection mechanisms.

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Around 700 employees in research, administration and infrastructure, and about 140 visiting scientists from 40 different countries are employed at the Helmholtz Centre for Infection Research.

Our scientists pursue research to expand our knowledge of the fundamental mechanisms behind medically relevant infectious diseases.

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The Helmholtz Centre for Infection Research

How do bacteria, viruses, parasites and fungi make us sick? How does our immune system defend our body?

These are the questions we at the HZI want to answer. Our goal: To set up the basis for new diagnostic tools, new active agents and new therapies against infectious diseases.

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3rd International HIPS Symposium

on 18 July 2013

on the Campus of the Saarland University


The HIPS SYMPOSIUM aims at bringing together renowed scientists and young investigators from three pharmaceutical communities: natural products, medicinal chemistry and drug delivery.

Event details

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Feature

Life between species - zoonoses

Plague, salmonellosis, rabies, SARS, Lyme disease, Creutzfeld-Jakob disease, and avian flu are only a few of a host of pathogens that can readily transfer from animals to humans – and vice versa. In the US, their bite transmits Yersinia pestis from plague-infested meerkats to domestic cats that in turn pass the bacterium on to their human owners. A rabid dog infects its owner via its saliva; a tick that feeds on the blood of borrelia-infected wildlife can transmit the bacterium to humans through its bite; influenza-infected migratory birds infect poultry, which in turn pass the virus on to the poultry keeper.

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Information for Students

  • Studies
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Our Partner Universities

Georg-August-Universität Göttingen

Leibniz Universität Hannover

Medizinische Hochschule Hannover

Otto-von-Guericke-Universität Magdeburg

Technische Universität Braunschweig

Tierärztliche Hochschule Hannover

University of Saarland

Master and Phd Theses

  • 11.02.2013
    Hauptsitz Braunschweig

    2 Masterarbeiten: Antibody Engineering in einer neuen Intrabody Facility

    Herstellung und in vitro Charakterisierung von intrazellulären Antikörpern für die Herstellung transgener Intrabody Mäuse. Intrazelluläre Antikörper werden sehr effizient für den knockdown von Proteinen eingesetzt. Am HZI wird eine Intrabody Facility, in der Intrabodies gegen Infektions-relevante Antigene hergestellt werden, aufgebaut. Der Schwerpunkt sind Intrabodies, die im ER exprimiert werden und transitorische Proteine (Z.B. Oberflächen-und intrazelluläre Rezeptoren, Golgi lokalisierte Enzyme) im ER zurückhalten und dadurch inaktivieren. Unser Ziel ist es, transgene Intrabody Mäuse herzustellen, welche die spezifischen Intrabodies konstitutiv oder regulierbar Gewebe-spezifisch exprimieren. Dabei wird die neue Intrabody Facility mit 2 Abteilungen (Rekombinante Antikörperselektion, Stefan Dübel, TU Braunschweig) und der transgenen Maus Abteilung (D.Wirth, HZI) eng zusammenarbeiten.

  • 16.03.2012

    Master Thesis - Immunregulation

  • 08.03.2012

    Master Thesis in Molecular Structural Biology

  • 16.12.2011

    Masters Thesis - Gene Regulation and Differentiation (Biology, Biochemistry, Biotechnology)

  • 14.10.2011

    Master Thesis - Structure based Infection Biology

  • 02.08.2011

    Master Thesis - Cellular Proteom Research

  • 08.09.2010

    Master Thesis at Molecular Diagnostics Laboratory

  • 04.12.2008

    Masters Thesis - Structural Biology

Headquarter

Helmholtz Centre for Infection Research
Inhoffenstraße 7
38124 Braunschweig
+49 531 6181-0
info@helmholtz-hzi.de

Branch

Helmholtz Institute for Pharmaceutical Research Saarland
Campus, Geb. C2.3
Universität des Saarlandes
66123 Saarbrücken
+49 681 302-70200
info.hips@helmholtz-hzi.de

Branch

TWINCORE
Zentrum für Experimentelle und Klinische Infektionsforschung
Feodor-Lynen-Str. 7
30625 Hannover
+49 511 220027-0
twincore@twincore.de

Study Centre

Study Centre Hannover
Feodor-Lynen-Straße 5
30625 Hannover
+49 511 1235950-0
healthstudy@helmholtz-hzi.de

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