Helmholtz-Zentrum für Infektionsforschung

Helmholtz-Zentrum für Infektionsforschung

Vollständige Publikationsliste der Gruppe Claus-Michael Lehr

 

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Ausgewählte Publikationen

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Hansen S, Slezer D, Schaefer UF and Kasting GB; (2011). An extended database of keratin binding. J Pharm Sci: 100 5, 1712-1726 PubMed

Ciana A, Meier K, Daum N, Gerbes S, Veith M, Lehr CM, Minetti G; (2010). A dynamic ratio of the alpha+ and alpha- isoforms of the tight junction protein ZO-1 is characteristic of Caco-2 cells and correlates with their degree of differentiation. Cell Biol Int.: 34 6, 669-678 PubMed

Leonard F, Collnot EM, Lehr CM; (2010). A Three-Dimensional Coculture of Enterocytes, Monocytes and Dendritic Cells To Model Inflamed Intestinal Mucosa in Vitro. Mol Pharm.: 7 6, 2103-2119 PubMed

Khvedelidze M, Mdzinarashvili T, Partskhaladze T, Nafee N, Schaefer UF, Lehr CM, Schneider M; (2010). Calorimetric and spectrophotometric investigation of PLGA Nanoparticles and their complex with DNA. J Therm Anal Calorim: 99, 337-348

Gaschen A, Lang D, Kalberer M, Savi M, Geiser T, Gazdhar A, Lehr CM, Bur M, Dommen J, Baltensperger U, Geiser M; (2010). Cellular responses after exposure of lung cell cultures to secondary organic aerosol particles. Environ Sci Technol.: 44 4, 1424-1430 PubMed

Hoppstädter J, Diesel B, Zarbock R, Breinig T, Monz D, Koch M, Meyerhans A, Gortner L, Lehr CM, Huwer H, Kiemer AK; (2010). Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages. Respir Res.: 11, 124 PubMed

Bur M, Huwer H, Muys L, Lehr CM; (2010). Drug transport across pulmonary epithelial cell monolayers: effects of particle size, apical liquid volume, and deposition technique. J Aerosol Med Pulm Drug Deliv.: 23 3, 119-127 PubMed

Rytting E, Bur M, Cartier R, Bouyssou T, Wang X, Krüger M, Lehr CM, Kissel T; (2010). In vitro and in vivo performance of biocompatible negatively-charged salbutamol-loaded nanoparticles. J Control Release: 141 1, 101-107 PubMed

Henning A, Schneider M, Nafee N, Muijs L, Rytting E, Wang X, Kissel T, Grafahrend D, Klee D, Lehr CM; (2010). Influence of particle size and material properties on mucociliary clearance from the airways. J Aerosol Med Pulm Drug Deliv.: 23 4, 233-241 PubMed

Hahn T, Hansen S, Neumann D, Kostka KH, Lehr CM, Muys L, Schaefer UF; (2010). Infrared densitometry: a fast and non-destructive method for exact stratum corneum depth calculation for in vitro tape-stripping. Skin Pharmacol Physiol.: 23 4, 183-192 PubMed

Hahn T, Schaefer UF, Lehr CM; (2010). Measuring Skin Absorption In Vitro. SOFW Journal: 136, 28-38

Santander-Ortega MJ, Stauner T, Loretz B, Ortega-Vinuesa JL, Bastos-González D, Wenz G, Schaefer UF, Lehr CM; (2010). Nanoparticles made from novel starch derivatives for transdermal drug delivery. J Control Release: 141 1, 85-92 PubMed

Muendoerfer M, Schaefer UF, Koenig P, Walk JS, Loos P, Balbach S, Eichinger T, Lehr CM; (2010). Online monitoring of transepithelial electrical resistance (TEER) in an apparatus for combined dissolution and permeation testing. Int J Pharm.: 392, 134-140 PubMed

Maurer F, Daum N, Schaefer UF, Lehr CM, Bauer P; (2010). Plant genetic factors for iron homeostasis affect iron bioavailability in Caco-2 cells. Food Research International: 43, 1661-1665

Philippi C, Loretz B, Schaefer UF, Lehr CM; (2010). Telomerase as an emerging target to fight cancer--opportunities and challenges for nanomedicine. J Control Release: 146 2, 228-240 PubMed

Hein S, Bur M, Kolb T, Muellinger B, Schaefer UF, Lehr CM; (2010). The Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) in vitro system: design and experimental protocol. Altern Lab Anim.: 38 4, 285-295 PubMed

Collnot EM, Baldes C, Schaefer UF, Edgar KJ, Wempe MF, Lehr CM; (2010). Vitamin E TPGS P-glycoprotein inhibition mechanism: influence on conformational flexibility, intracellular ATP levels, and role of time and site of access. Mol Pharm.: 7 3, 642-651 PubMed

Melero A, Lehr CM, Schäfer UF, Garrigues TM; (2010). Wistar rat skin as surrogate for human skin in nortriptyline hydrochloride patch studies. Int J Pharm.: 384, 137-139 PubMed

Bur M, Rothen-Rutishauser B, Huwer H, Lehr CM; (2009). A novel cell compatible impingement system to study in vitro drug absorption from dry powder aerosol formulations. Eur J Pharm Biopharm.: 72 2, 350-357 PubMed

Lehr CM; (2009). Biological barriers and nanomedicine--timely challenges in advanced drug delivery research. Eur J Pharm Biopharm.: 72 2, 287-288 PubMed

Schmitt S, Schaefer UF, Doebler L, Reichling J; (2009). Cooperative interaction of monoterpenes and phenylpropanoids on the in vitro human skin permeation of complex composed essential oils. Planta Med.: 75 13, 1381-1385 PubMed

Meier K, Lehr CM, Daum N; (2009). Differentiation potential of human pancreatic stem cells for epithelial- and endothelial-like cell types. Ann Anat.: 191 1, 70-82 PubMed

Beisner J, Dong M, Taetz S, Piotrowska K, Kleideiter E, Friedel G, Schaefer U, Lehr CM, Klotz U, Mürdter TE; (2009). Efficient telomerase inhibition in human non-small cell lung cancer cells by liposomal delivery of 2'-O-methyl-RNA. J Pharm Sci.: 98 5, 1765-1774 PubMed

Taetz S, Bochot A, Surace C, Arpicco S, Renoir JM, Schaefer UF, Marsaud V, Kerdine-Roemer S, Lehr CM, Fattal E; (2009). Hyaluronic acid-modified DOTAP/DOPE liposomes for the targeted delivery of anti-telomerase siRNA to CD44-expressing lung cancer cells. Oligonucleotides.: 19 2, 103-116 PubMed

Bur M, Henning A, Hein S, Schneider M, Lehr CM; (2009). Inhalative nanomedicine--opportunities and challenges. Inhal Toxicol.: 21, 137-143 PubMed

Melero A, Garrigues TM, Alós M, Kostka KH, Lehr CM, Schaefer UF; (2009). Nortriptyline for smoking cessation: release and human skin diffusion from patches. Int J Pharm.: 378, 101-107 PubMed

Bhardwaj V, Ankola DD, Gupta SC, Schneider M, Lehr CM, Kumar MN; (2009). PLGA nanoparticles stabilized with cationic surfactant: safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat. Pharm Res.: 26 11, 2495-2503 PubMed

Henning A, Schäfer UF, Neumann D; (2009). Potential pitfalls in skin permeation experiments: Influence of experimental factors and subsequent data evaluation. EJPB Special issue paper: 72 2, 324-331 PubMed

Nafee N, Schneider M, Schaefer UF, Lehr CM; (2009). Relevance of the colloidal stability of chitosan/PLGA nanoparticles on their cytotoxicity profile. Int J Pharm.: 381 2, 130-139 PubMed

Taetz S, Nafee N, Beisner J, Piotrowska K, Baldes C, Mürdter TE, Huwer H, Schneider M, Schaefer UF, Klotz U, Lehr CM; (2009). The influence of chitosan content in cationic chitosan/PLGA nanoparticles on the delivery efficiency of antisense 2'-O-methyl-RNA directed against telomerase in lung cancer cells. Eur J Pharm Biopharm.: 72 2, 358-369 PubMed

Hansen S, Naegel A, Heisig M, Wittum G, Neumann D, Kostka KH, Meiers P, Lehr CM, Schaefer UF; (2009). The role of corneocytes in skin transport revised--a combined computational and experimental approach. Pharm Res.: 26 6, 1379-1397 PubMed

Collnot EM, Baldes C, Wempe MF, Hyatt J, Navarro L, Edgar KJ, Schaefer UF, Lehr CM; (2006). Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers. J Control Release: 111, 35-40 PubMed

Stracke F, Weiss B, Lehr CM, König K, Schaefer UF, Schneider M; (2006). Multiphoton microscopy for the investigation of dermal penetration of nanoparticle-borne drugs. J Invest Dermatol.: 126 10, 2224-2233 PubMed

Ravi Kumar MN, Bakowsky U, Lehr CM; (2004). Preparation and characterization of cationic PLGA nanospheres as DNA carriers. Biomaterials: 25 10, 1771-1777 PubMed

Fuchs S, Hollins AJ, Laue M, Schaefer UF, Roemer K, Gumbleton M, Lehr CM; (2003). Differentiation of human alveolar epithelial cells in primary culture: morphological characterization and synthesis of caveolin-1 and surfactant protein-C. Cell Tissue Res.: 311 1, 31-45 PubMed

Wagner H, Kostka KH, Lehr CM, Schaefer UF; (2002). Human skin penetration of flufenamic acid: in vivo/in vitro correlation (deeper skin layers) for skin samples from the same subject. J Invest Dermatol.: 118 3, 540-544 PubMed

Lamprecht A, Ubrich N, Yamamoto H, Schäfer U, Takeuchi H, Maincent P, Kawashima Y, Lehr CM ; (2001). Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J Pharmacol Exp Ther.: 299 2, 775-781 PubMed

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21.05.2012