Helmholtz-Zentrum für Infektionsforschung

Helmholtz-Zentrum für Infektionsforschung

Publikationen der Arbeitsgruppe

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Pistorius,D.; Müller,Rolf*; (2012). Discovery of the Rhizopodin Biosynthetic Gene Cluster in Stigmatella aurantiaca Sg a15 by Genome Mining1. ChemBioChem: 13 3, 416-426

Barbier,J.; Jansen,R.; Irschik,H.; Benson,S.; Gerth,Klaus*; Bohlendorf,B.; Hofle,G.; Reichenbach,H.; Wegner,J.; Zeilinger,C.; Kirschning,A.; Müller,Rolf*; (2012). Isolation and Total Synthesis of Icumazoles and Noricumazoles-Antifungal Antibiotics and Cation-Channel Blockers from Sorangium cellulosum1. Angewandte Chemie International Edition: 51 5, 1256-1260

Xiao,Y.; Gerth,Klaus*; Müller,Rolf*; Wall,D.; (2012). Myxobacterium-Produced Antibiotic TA (Myxovirescin) Inhibits Type II Signal Peptidase1. Antimicrobial Agents and Chemotherapy: 56 4, 2014-2021

Cortina,N.S.; Krug,D.; Plaza,A.; Revermann,O.; Müller,Rolf*; (2012). Myxoprincomide: a natural product from Myxococcus xanthus discovered by comprehensive analysis of the secondary metabolome1. Angewandte Chemie International Edition: 51 3, 811-816

Friedl,T.; Brinkmann,N.; Mohr,Kathrin I.*; (2011). Algae (Eukaryotic).: Encyclopedia of Geobiology, Encyclopedia of Earth Sciences Series. Reitner,J.; Thiel,V.; (Ed.). Springer, The Netherlands, 10-20

Mohr,Kathrin I.*; Brinkmann,N.; Friedl,T.; (2011). Cyanobacteria.: Encyclopedia of Geobiology, Encyclopedia of Earth Sciences Series. Reitner,J.; Tiehl,V.; (Ed.). Springer, The Netherlands, 306-311

Brinkmann,N.; Friedl,T.; Mohr,Kathrin I.*; (2011). Diatoms.: Encyclopedia of Geobiology, Encyclopedia of Earth Sciences Series. Reitner,J.; Thiel,V.; (Ed.). Springer, The Netherlands, 326-330

Steinmetz,H.; Gerth,Klaus*; Jansen,R.; Schlager,N.; Dehn,R.; Reinecke,S.; Kirschning,A.; Müller,Rolf*; (2011). Elansolid A, a Unique Macrolide Antibiotic from Chitinophaga sancti Isolated as Two Stable Atropisomers. Angewandte Chemie International Edtion: 50 2, 532-536

Jansen,Rolf*; Gerth,Klaus*; Steinmetz,Heinrich*; Reinecke,S.; Kessler,W.; Kirschning,A.; Müller,Rolf*; (2011). Elansolid A3, a Unique p-Quinone Methide Antibiotic from Chitinophaga sancti. Chemistry: 17 28, 7739-7744

Abdel-Basset,R.; Friedl,T.; Mohr,Kathrin I.*; Rybalka,N.; Martin,W.; (2011). High growth rate, photosynthesis rate and increased hydrogen(ases) in manganese deprived cells of a newly isolated Nostoc-like cyanobacterium (SAG 2306). International Journal of Hydrogen Energy: 36 19, 12200-12210

Kopp,M.; Irschik,Herbert*; Gemperlein,K.; Buntin,K.; Meiser,P.; Weissman,K.J.; Bode,H.B.; Müller,Rolf*; (2011). Insights into the complex biosynthesis of the leupyrrins in Sorangium cellulosum So ce690. Molecular BioSystems: 7 5, 1549-1563 HZI-Repositorium PubMed

Okanya,P.W.; Mohr,K.I.; Gerth,Klaus*; Jansen,Rolf*; Müller,Rolf*; (2011). Marinoquinolines A-F, Pyrroloquinolines from Ohtaekwangia kribbensis (Bacteroidetes). Journal of Natural Products: 74 4, 603-608

Dehn,R.; Katsuyama,Y.; Weber,A.; Gerth,Klaus*; Jansen,Rolf*; Steinmetz,Heinrich*; Höfle,G.; Müller,Rolf*; Kirschning,A.; (2011). Molecular basis of elansolid biosynthesis: evidence for an unprecedented quinone methide initiated intramolecular diels-alder cycloaddition/macrolactonization. Angewandte Chemie International Edition: 50 17, 3882-3887

Dehn,R.; Katsuyama,Y.; Weber,A.; Gerth,Klaus*; Jansen,Rolf*; Steinmetz,Heinrich*; Höfle,Gerhard*; Müller,Rolf*; Kirschning,A.; (2011). Molecular basis of elansolid biosynthesis: evidence for an unprecedented quinone methide inititiated intramolecular Diels-Alder cycloaddition / macrolactonization. Angewandte Chemie: 50 2, 532-536

Srivastava,A.; Talaue,M.; Liu,S.; Degen,D.; Ebright,R.Y.; Sineva,E.; Chakraborty,A.; Druzhinin,S.Y.; Chatterjee,S.; Mukhopadhyay,J.; Ebright,Y.W.; Zozula,A.; Shen,J.; Sengupta,S.; Niedfeldt,R.R.; Xin,C.; Kaneko,T.; Irschik,Herbert*; Jansen,Rolf*; Donadio,S.; Connell,N.; Ebright,R.H.; (2011). New target for inhibition of bacterial RNA polymerase: 'switch region'. Current Opinion in Microbiology: 14 5, 532-543

Zander,W.; Mohr,K.I.; Gerth,Klaus*; Jansen,R.; Müller,Rolf*; (2011). p-Hydroxyacetophenone Amides from Cystobacter ferrugineus , strain Cb G35. Journal of Natural Products: 74 6, 1358-1363

Capell,A.; Liebscher,S.; Fellerer,K.; Brouwers,N.; Willem,M.; Lammich,S.; Gijselinck,I.; Bittner,T.; Carlson,A.M.; Sasse,Florenz*; Kunze,B.; Steinmetz,H.; Jansen,Rolf*; Dormann,D.; Sleegers,K.; Cruts,M.; Herms,J.; Van,Broeckhoven C.; Haass,C.; (2011). Rescue of Progranulin Deficiency Associated with Frontotemporal Lobar Degeneration by Alkalizing Reagents and Inhibition of Vacuolar ATPase. Journal of Neuroscience: 31 5, 1885-1894

Zander,W.; Gerth,Klaus*; Mohr,K.I.; Kessler,W.; Jansen,Rolf*; Müller,Rolf*; (2011). Roimatacene, an antibiotic against gram-negative bacteria isolated from cystobacter Cb G35 (myxobacteria). Chemistry - A European Journal: 17 28, 7875-7881

Li,Z.; Kessler,Wolfgang; van den,Heuvel Joop*; Rinas,Ursula*; (2011). Simple defined autoinduction medium for high-level recombinant protein production using T7-based Escherichia coli expression systems. Applied Microbiology and Biotechnology: 91 4, 1203-1213 HZI-Repositorium PubMed

Keck,M.; Gisch,N.; Moll,H.; Vorholter,F.J.; Gerth,Klaus*; Kahmann,U.; Lissel,M.; Lindner,B.; Niehaus,K.; Holst,O.; (2011). Unusual Outer Membrane Lipid Composition of the Gram-negative, Lipopolysaccharide-lacking Myxobacterium Sorangium cellulosum So ce56. Journal of Biological Chemistry: 286 15, 12850-12859

Irschik,Herbert*; Kopp,M.; Weissman,K.J.; Buntin,K.; Piel,J.; Müller,Rolf*; (2010). Analysis of the sorangicin gene cluster reinforces the utility of a combined phylogenetic/retrobiosynthetic analysis for deciphering natural product assembly by trans-AT PKS. ChemBioChem: 11 13, 1840-1849

Buntin,K.; Irschik,Herbert*; Weissman,K.J.; Luxenburger,E.; Blöcker,Helmut*; Müller,Rolf*; (2010). Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity. Chemistry and Biology: 17 4, 342-356

Kunze,B.; Reck,M.; Dotsch,A.; Lemme,A.; Schummer,D.; Irschik,Herbert*; Steinmetz,H.; Wagner-Döbler,Irene*; (2010). Damage of Streptococcus mutans biofilms by carolacton, a secondary metabolite from the myxobacterium Sorangium cellulosum. BMC Microbiology: 10, 199

Menche,D.; Li,P.; Irschik,Herbert*; (2010). Design, synthesis and biological evaluation of simplified analogues of the RNA polymerase inhibitor etnangien. Bioorganic and Medicinal Chemistry Letters: 20 3, 939-941

Garcia,R.; Gerth,Klaus*; Stadler,M.; Dogma,I.J.,Jr.; Müller,Rolf*; (2010). Expanded phylogeny of myxobacteria and evidence for cultivation of the 'unculturables'. Molecular Phylogenetics and Evolution: 57 2, 878-887

Nicolas,L.; Anderl,T.; Sasse,Florenz*; Steinmetz,H.; Jansen,Rolf*; Hofle,G.; Laschat,S.; Taylor,R.E.; (2010). Gephyronic Acid, a Missing Link between Polyketide Inhibitors of Eukaryotic Protein Synthesis (Part I): Structural Revision and Stereochemical Assignment of Gephyronic Acid. Angewandte Chemie International Edition: 50 4, 938-941

Anderl,T.; Nicolas,L.; Munkemer,J.; Baro,A.; Sasse,Florenz*; Steinmetz,H.; Jansen,Rolf*; Hofle,G.; Taylor,R.E.; Laschat,S.; (2010). Gephyronic Acid, a Missing Link between Polyketide Inhibitors of Eukaryotic Protein Synthesis (Part II): Total Synthesis of Gephyronic Acid. Angewandte Chemie International Edition: 50 4, 942-945

Brodmann,T.; Janssen,D.; Sasse,Florenz*; Irschik,Herbert*; Jansen,Rolf*; Müller,Rolf*; Kalesse,Markus*; (2010). Isolation and synthesis of chivotriene, a chivosazole shunt product from Sorangium cellulosum. European Journal of Organic Chemistry: 27, 5155-5159

Niggemann,Jutta*; Gerth,Klaus*; Horstmann,N.; Bauerochse,A.; Kalesse,Markus*; (2010). Kultivierung und Identifizierung des endophytischen Pilzes Penicillium janthinellum Biourge aus dem Großen Moor bei Uchte (Niedersachsen) und Charakterisierung eines sekundären Stoffwechselproductes. Telma: 40, 245-254

Vilchez,R.; Lemme,A.; Ballhausen,B.; Thiel,V.; Schulz,S.; Jansen,Rolf*; Sztajer,Helena*; Wagner-Döbler,Irene*; (2010). Streptococcus mutans Inhibits Candida albicans hyphal formation by the fatty acid signaling molecule trans-2-decenoic acid (SDSF). ChemBioChem: 11 11, 1552-1562

Bulow,L.; Nickeleit,I.; Girbig,A.K.; Brodmann,T.; Rentsch,A.; Eggert,U.; Sasse,Florenz*; Steinmetz,Heinrich*; Frank,Ronald*; Carlomagno,T.; Malek,N.P.; Kalesse,Markus*; (2010). Synthesis and biological characterization of argyrin F. ChemMedChem: 5 6, 832-836

Nawrath,T.; Gerth,Klaus*; Müller,Rolf*; Schulz,S.; (2010). The biosynthesis of the aroma volatile 2-methyltetrahydrothiophen-3-one in the bacterium Chitinophaga Fx7914. ChemBioChem: 11 13, 1914-1919 PubMed

Arp,G.; Bissett,A.; Brinkmann,N.; Cousin,S.; de Beer,D.; Friedl,T.; Mohr,Kathrin I.*; Neu,T.R.; Reimer,A.; Shiraishi,F.; Stackebrandt,E.; Zippel,B.; (2010). Tufa-forming biofilms of German karstwater streams: Microorganisms, exopolymers, hydrochemistry and calcification. Geological Society Stecial Publication: 336, 83-118

Nawrath,T.; Gerth,Klaus*; Müller,Rolf*; Schulz,S.; (2010). Volatile methyl esters of medium chain length from the bacterium Chitinophaga Fx7914. Chemistry and Biodiversity: 7 9, 2228-2253 PubMed

Shushni,M.A.; Mentel,R.; Lindequist,U.; Jansen,Rolf*; (2009). Balticols A-F, new naphthalenone derivatives with antiviral activity, from an ascomycetous fungus. Chemistry and Biodiversity: 6 2, 127-137

Müller,Rolf*; (2009). Biosynthesis and heterologous production of epothilones.: The Epothilones, an Outstanding Family of Anti-Tumor Agents. Mulzer,J.; (Ed.). New York : Springer, 29-533

Jansen,Rolf*; Irschik,Herbert*; Huch,V.; Schummer,D.; Steinmetz,Heinrich*; Bock,M.; Schmidt,T.; Kirschning,A.; Müller,Rolf*; (2009). Carolacton - a macrolide ketocarbonic acid reducing biofilm formation by the caries- and endocarditis-associated bacterium Streptococcus mutans. European Journal of Organic Chemistry: 7, 1284-1289 HZI-Repositorium

Diestel,R.; Irschik,Herbert*; Jansen,Rolf*; Khalil,M.W.; Reichenbach,H.; Sasse,Florian*; (2009). Chivosazoles A and F, cytostatic macrolides from myxobacteria, interfere with actin. ChemBioChem: 10 18, 2900-2903 HZI-Repositorium PubMed

Jensen,N.A.; Gerth,Klaus*; Grotjohann,T.; Kapp,D.; Keck,M.; Niehaus,K.; (2009). Establishment of a high content assay for the identification and characterisation of bioactivities in crude bacterial extracts that interfere with the eukaryotic cell cycle. Journal of Biotechnology: 140 1-2, 124-134

Suryanarayanan,T.S.; Thirunavukkarasu,N.; Gowindarajulu,M.B.; Sasse,Florian*; Jansen,Rolf*; Murali,T.S.; (2009). Fungal endophytes and bioprospecting. Fungal Biology Reviews: 23 1-2, 9-19 HZI-Repositorium

Zollner,A.; Dragan,C.A.; Pistorius,D.; Müller,Rolf*; Bode,H.B.; Peters,F.T.; Maurer,H.H.; Bureik,M.; (2009). Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid. Biological Chemistry: 390 4, 313-317

Zainuddin,E.N.; Jansen,Rolf*; Nimtz,Manfred*; Wray,Victor*; Preisitsch,M.; Lalk,M.; Mundt,S.; (2009). Lyngbyazothrins A-D, antimicrobial cyclic undecapeptides from the cultured Cyanobacterium lyngbya sp. Journal of Natural Products: 72 8, 1373-1378

Perlova,O.; Gerth,Klaus*; Kuhlmann,S.; Zhang,Y.; Müller,Rolf*; (2009). Novel expression hosts for complex secondary metabolite megasynthetases: Production of myxochromide in the thermopilic isolate Corallococcus macrosporus GT-2. Microbial Cell Factories: 8 1, 1

Rachid,S.; Gerth,Klaus*; Müller,Rolf*; (2009). NtcA-A negative regulator of secondary metabolite biosynthesis in Sorangium cellulosum. Journal of Biotechnology: 140 1-2, 135-142

Garcia,R.O.; Reichenbach,H.; Ring,M.W.; Müller,Rolf*; (2009). Phaselicystis flava gen. nov., sp. nov., an arachidonic acid-containing soil myxobacterium, and the description of Phaselicystidaceae fam. nov. International Journal of Systematic and Evolutionary Microbiology: 59 Pt 6, 1524-1530

Hagelüken,G.; Albrecht,S.C.; Steinmetz,Heinrich*; Jansen,Rolf*; Heinz,Dirk W.*; Kalesse,Markus*; Schubert,Wolf-Dieter*; (2009). The absolute configuration of rhizopodin and its inhibition of actin polymerization by dimerization. Angewandte Chemie International Edition: 48 3, 595-598

Rachid,S.; Scharfe,Maren*; Blöcker,Helmut*; Weissman,K.J.; Müller,Rolf*; (2009). Unusual chemistry in the biosynthesis of the antibiotic chondrochlorens. Chemistry and Biology: 16 1, 70-81

Sandmann,A.; Frank,B.; Müller,Rolf*; (2008). A transposon-based strategy to scale up myxothiazol production in myxobacterial cell factories. Journal of Biotechnology: 135 3, 255-261

Wenzel,S.C.; Bode,H.B.; Kochems,I.; Müller,Rolf*; (2008). A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin. ChemBioChem: 9 16, 2711-2721

Dwivedi,D.; Jansen,Rolf*; Molinari,Gabriella*; Nimtz,Manfred*; Johri,B.N.; Wray,Victor*; (2008). Antimycobacterial serratamolides and diacyl peptoglucosamine derivatives from Serratia sp.. Journal of Natural Products: 71 4, 637-641

Nickeleit,I.; Zender,S.; Sasse,Florenz*; Geffers,Robert*; Brandes,G.; Sorensen,I.; Steinmetz,Heinrich*; Kubicka,S.; Carlomagno,T.; Menche,D.; Gutgemann,I.; Buer,J.; Gossler,A.; Manns,M.P.; Kalesse,Markus*; Frank,Ronald*; Malek,N.P.; (2008). Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition. 14 1, 23-35

Gerth,Klaus*; Steinmetz,Heinrich*; Höfle,Gerhard*; Jansen,Rolf*; (2008). Chlorotonil A, a macrolide with a unique gem-dichloro-1,3-dione functionality from Sorangium cellulosum So ce1525. Angewandte Chemie: 120 610, 613 HZI-Repositorium PubMed

Gerth,Klaus*; Steinmetz,Heinrich*; Höfle,Gerhard*; Jansen,Rolf*; (2008). Chlorotonil A, a macrolide with a unique gem-dichloro-1,3-dione functionality from Sorangium cellulosum So ce1525. Angewandte Chemie International Edition: 47 600, 602 HZI-Repositorium PubMed

Weissman,K.J.; Müller,Rolf*; (2008). Crystal structure of a molecular assembly line. Angewandte Chemie International Edition: 47 44, 8344-8346

Krug,D.; Zurek,G.; Revermann,O.; Vos,M.; Velicer,G.J.; Müller,Rolf*; (2008). Discovering the hidden secondary metabolome of Myxococcus xanthus: a study of intraspecific diversity. Applied in Environmental Microbiology: 74 10, 3058-3068

Reichenbach,Hans*; Gerhard,Höfle*; (2008). Discovery and development of the epothilones: A novel class of antineoplastic drugs. Drugs in R and D: 9 1, 1-10 HZI-Repositorium PubMed

Meiser,P.; Weissman,K.J.; Bode,H.B.; Krug,D.; Dickschat,J.S.; Sandmann,A.; Müller,Rolf*; (2008). DKxanthene biosynthesis--understanding the basis for diversity-oriented synthesis in myxobacterial secondary metabolism. Chemistry and Biology: 15 8, 771-781

Krug,D.; Zurek,G.; Schneider,B.; Garcia,R.; Müller,Rolf*; (2008). Efficient mining of myxobacterial metabolite profiles enabled by liquid chromatography-electrospray ionisation-time-of-flight mass spectrometry and compound-based principal component analysis. Analytica Chimica Acta: 624 1, 97-106

Fu,J.; Wenzel,S.C.; Perlova,O.; Wang,J.; Gross,F.; Tang,Z.; Yin,Y.; Stewart,A.F.; Müller,Rolf*; Zhang,Y.; (2008). Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition. Nucleic Acids Research: 36 17, e113

Mulzer,J.; Altmann,K.-H.; Höfle,Gerhard*; Müller,Rolf`*; Prantz,K.; (2008). Epothilones - A fascinating family of microtubule stabilizing antitumor agents. Comptes Rendus Chimie: 11 11-12, 1336-1368

Perez,J.; Castaneda-Garcia,A.; Jenke-Kodama,H.; Müller,Rolf*; Munoz-Dorado,J.; (2008). Eukaryotic-like protein kinases in the prokaryotes and the myxobacterial kinome. Proceedings of the National Academy of Siences USA: 105 41, 15950-15955

Jenke-Kodama,H.; Müller,Rolf*; Dittmann,E.; (2008). Evolutionary Mechanisms underlying secondary metabolite diversity.: Progress in Drug Research. Petersen,F.; Amstutz,R.; (Ed.)., 121-140

Binz,T.M.; Wenzel,S.C.; Schnell,H.J.; Bechthold,A.; Müller,Rolf*; (2008). Heterologous expression and genetic engineering of the phenalinolactone biosynthetic gene cluster by using red/ET recombineering. ChemBioChem: 9 3, 447-454 Volltext HZI-Repositorium

Nawrath,T.; Dickschat,J.S.; Müller,Rolf*; Jiang,J.; Cane,D.E.; Schulz,S.; (2008). Identification of (8S,9S,10S)-8,10-dimethyl-1-octalin, a key intermediate in the biosynthesis of geosmin in bacteria. Journal of the American Chemical Society: 130 2, 430-431 PubMed

Höfle,Gerhard*; Irschik,Herbert*; (2008). Isolation and Biosynthesis of Aurachin P and 5-Nitroresorcinol from Stigmatella erecta. Journal of Natural Products: 71 11, 1946-1948

Jansen,Rolf*; Steinmetz,Heinrich*; Sasse,Florenz*; Schubert,Wolf-Dieter*; Hagelüken,Gregor*; Albrecht,S.C.; Müller,Rolf*; (2008). Isolation and structure revision of the actin-binding macrolide rhizopodin from Myxococcus stipitatus (Myxobacteria). Tetrahedron Letters: 49, 5796-5799

Knauber,T.; Doss,S.D.; Gerth,Klaus*; Perlova,O.; Müller,Rolf*; Treuner-Lange,A.; (2008). Mutation in the rel gene of Sorangium cellulosum affects morphological and physiological differentiation. Molecular Microbiology: 69 1, 254-266

Li,Y.; Weissman,K.J.; Müller,Rolf*; (2008). Myxochelin biosynthesis: direct evidence for two- and four-electron reduction of a carrier protein-bound thioester. Journal of the American Chemica Society: 130 24, 7554-7555

Buntin,K.; Rachid,S.; Scharfe,Maren*; Blöcker,Helmut*; Weissman,K.J.; Müller,Rolf*; (2008). Production of the antifungal isochromanone ajudazols A and B in Chondromyces crocatus Cm c5: biosynthetic machinery and cytochrome P450 modifications. Angewandte Chemie International Edition: 47 24, 4595-4599

Weissman,K.J.; Müller,Rolf*; (2008). Protein-protein interactions in multienzyme megasynthetases. ChemBioChem: 9 6, 826-848

Feklistov,A.; Mekler,V.; Jiang,Q.; Westblade,L.F.; Irschik,Herbert*; Jansen,Rolf*; Mustaev,A.; Darst,S.A.; Ebright,R.H.; (2008). Rifamycins do not function by allosteric modulation of binding of Mg2+ to the RNA polymerase active center. Proceedings of the National Academy of the United States of America: 105 39, 14820-14825

Gerth,Klaus*; Perlova,O.; Müller,Rolf*; (2008). Sorangium cellulosum.: Myxobacteria: Multicellularity and Differentiation. Whitmorth,D.E.; (Ed.). Washington D.C. : ASM Press, 329-348

Menche,Dirk*; Arikan,F.; Perlova,O.; Horstmann,Nicole*; hlbrecht,W.; Wenzel,S.C.; Jansen,Rolf*; Irschik,Herbert*; Müller,Rolf*; (2008). Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum. Journal of the American Chemical Society: 130 43, 14234-14243

Bock,M.; Buntin,K.; Müller,Rolf*; irschning,A.; (2008). Stereochemical determination of thuggacins A-C, highly active antibiotics from the myxobacterium Sorangium cellulosum. Angewandte Chemie International Edition: 47 12, 2308-2311

Petkovic,H.; Sandmann,A.; Challis,I.R.; Hecht,Hans-Jürgen*; Silakowski,B.; Low,L.; Beeston,N.; Kuscer,E.; Garcia-Bernardo,J.; Leadlay,P.F.; Kendrew,S.G.; Wilkinson,B.; Müller,Rolf*; (2008). Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase. Organic and Biomolecular Chemistry: 6 3, 500-506

Mukhopadhyay,J.; Das,K.; Ismail,S.; Koppstein,D.; Jang,M.; Hudson,B.; Sarafianos,S.; Tuske,S.; Patel,J.; Jansen,Rolf*; Irschik,Herbert*; Arnold,E.; Ebright,R.H.; (2008). The RNA polymerase "switch region" is a target for inhibitors. Cell: 135 2, 295-307

Meiser,P.; Müller,Rolf*; (2008). Two functionally redundant Sfp-type 4'-phosphopantetheinyl transferases differentially activate biosynthetic pathways in Myxococcus xanthus. ChemBioChem: 9 10, 1549-1553

Simunovic,V.; Müller,Rolf*; (2007). 3-hydroxy-3-methylglutaryl-CoA-like synthases direct the formation of methyl and ethyl side groups in the biosynthesis of the antibiotic myxovirescin A. ChemBioChem: 8 5, 497-500

Krug,D.; Zurek,G.; Schneider,B.; Bössmann,C.; Müller,Rolf*; (2007). Analysis of secondary metabolites from myxobacteria using ESI-TOF-MS and PCA. The Applications Book: March 2007, 41-42

Menche,Dirk*; Hassfeld,J.; Steinmetz,Heinrich*; Huss,M.; Wieczorek,H.; Sasse,Florian*; (2007). Archazolid-7-O//b//-d-glucopyranosid: Isolation, structural elucidation and solution conformation of a novel V-ATPase inhibitor from the Myxobacterium / Cystobacter violaceus. European Journal of Organic Chemistry: 2007, 1196-1202 HZI-Repositorium

Martens,T.; Gram,L.; Grossart,H.P.; Kessler,D.; Müller,Rolf*; Simon,M.; Wenzel,S.C.; Brinkhoff,T.; (2007). Bacteria of the Roseobacter clade show potential for secondary metabolite production. Microbial Ecology: 54 1, 31-42

Rachid,S.; Krug,D.; Weissman,K.J.; Müller,Rolf*; (2007). Biosynthesis of (R)-beta-tyrosine and its incorporation into the highly cytotoxic chondramides produced by Chondromyces crocatus. Journal of Biological Chemistry: 282 30, 21810-21817

Dickschat,J.S.; Nawrath,T.; Thiel,V.; Kunze,Brigitte*; Müller,Rolf*; Schulz,S.; (2007). Biosynthesis of the off-flavor 2-methylisoborneol by the myxobacterium Nannocystis exedens. Angewandte Chemie International Edition: 46 43, 8287-8290 Volltext HZI-Repositorium

Bui,H.T.N.; Jansen,Rolf*; Pham,H.T.L.; Mundt,S.; (2007). Carbamidocyclophanes A-E, chlorinated paracyclophanes with cytotoxic and antibiotic activity from the Vietnamese cynobacterium Nostoc. sp.. Journal of Natural Products: 70 4, 499-503

Janssen,D.; Albert,D.; Jansen,Rolf*; Müller,Rolf*; Kalesse,Markus*; (2007). Chivosazole A - elucidation of the absolute and relative configuration. Angewandte Chemie - International Edition: 46 26, 4898-4901

Schneiker,S.; Perlova,O.; Kaiser,O.; Gerth,Klaus*; Alici,A.; Altmeyer,M.O.; Bartels,D.; Bekel,T.; Beyer,S.; Bode,E.; Bode,H.B.; Bolten,C.J.; Choudhuri,J.V.; Doss,S.; Elnakady,Y.A.; Frank,B.; Gaigalat,L.; Goesmann,A.; Groeger,C.; Gross,F.; Jelsbak,L.; Jelsbak,L.; Kalinowski,J.; Kegler,C.; Knauber,T.; Konietzny,S.; Kopp,M.; Krause,L.; Krug,D.; Linke,B.; Mahmud,T.; Martinez-Arias,R.; McHardy,A.C.; Merai,M.; Meyer,F.; Mormann,S.; Muoz-Dorado,J.; Perez,J.; Pradella,S.; Rachid,S.; Raddatz,G.; Rosenau,F.; Rückert,C.; Sasse,Florian*; Scharfe,Maren*; Schuster,S.C.; Suen,G.; Treuner-Lange,A.; Velicer,G.J.; Vorhölter,F.-J.; Weissmann,K.J.; Welch,R.D.; Wenzel,S.C.; Whithworth,D.E.; Wilhelm,S.; Wittmann,C.; Blöcker,Helmut*; Pühler,A.; Müller,Rolf*; (2007). Complete genome sequence of the myxobacterium Sorangium cellulosum. Nature Biotechnology: 25 11, 1281-1289

Zainuddin,E.N.; Mentel,R.; Wray,Victor*; Jansen,Rolf*; Nimtz,Manfred*; Lalk,M.; Mundt,S.; (2007). Cyclic depsipeptides, ichthyopeptins A and B, from Microcystis ichthyoblabe. Journal of Natural Products: 70 7, 1084-1088 HZI-Repositorium PubMed

Rachid,S.; Gerth,Klaus*; Kochems,I.; Müller,Rolf*; (2007). Deciphering regulatory mechanisms for secondary metabolite production in the myxobacterium Sorangium cellulosum so ce56. Molecular Microbiology: 63 6, 1783-1796

Irschik,Herbert*; Schummer,D.; Höfle,Gerhard*; Reichenbach,Hans*; Steinmetz,Heinrich*; Jansen,Rolf; (2007). Etnangien, a macrolide-polyene antibiotic from Sorangium cellulosum that inhibits nucleic acid polymerases. Journal of Natural Products: 70 6, 1060-1063

Elnakady,Y.A.; Rohde,Manfred*; Sasse,Florian*; Backes,C.; Keller,A.; Lenhof,H.-P.; Weissman,K.J.; Müller,Rolf*; (2007). Evidence for the mode of the highly cytotoxic Streptomyces polyketide Kendomycin. ChemBioChem: 8 11, 1261-1272

Frank,B.; Wenzel,S.C.; Bode,H.B.; Scharfe,Maren*; Blöcker,Helmut*; Müller,Rolf*; (2007). From genetic diversity to metabolic unity: Studies on the biosynthesis of Aurafurones and Aurafuron-like structures in Myxobacteria and Streptomycetes. Journal of Molecular Biology: 374 1, 24-38

Backes,C.; Keller,A.; Kuentzer,J.; Kneissl,B.; Comtesse,N.; Elnakady,Y.A.; Müller,Rolf*; Meese,E.; Lenhof,H.P.; (2007). GeneTrail--advanced gene set enrichment analysis. Nucleic Acids Research: 35 Web Server issue, W186-W192 HZI-Repositorium

Bode,H.B.; Meiser,P.; Klefisch,T.; Cortina,N.S.; Krug,D.; Gohring,A.; Schwar,G.; Mahmud,T.; Elnakady,Y.A.; Müller,Rolf*; (2007). Mutasynthesis-derived myxalamids and origin of the isobutyryl-CoA starter unit of myxalamid B. ChemBioChem: 8 17, 2139-2144

Simunovic,V.; Müller,Rolf*; (2007). Mutational analysis of the myxovirescin biosynthetic gene cluster reveals novel insights into the functional elaboration of polyketide backbones. ChemBioChem: 8 11, 1273-1280

Wenzel,S.; Müller,Rolf*; (2007). Myxobacterial nature product assembly lines: Fascinating examples of curious biochemistry. Natural Products Reports: 24, 1211-1224

Gerth,Klaus*; Irschik,Herbert*; Jansen,Rolf*; Kunze,Brigitte*; Müller,Rolf*; Sasse,Florian*; (2007). Myxobakterien, vom Aussenseiter zum Geheimfavoriten.: Vorbild Natur. Kreysa,D.Sell; (Ed.). Frankfurt am Main : Dechema e.V., 64-71

Bode,H.B.; Müller,Rolf*; (2007). Reversible sugar transfer by glycosyltransferases as a tool for natural product (bio)synthesis. Angewandte Chemie International Edition: 46 13, 2147-2150

Sharma,A.; Jansen,Rolf*; Nimtz,Manfred*; Johri,B.N.; Wray,Victor*; (2007). Rhamnolipids from the rhizosphere bacterium Pseudomonas sp. GRP(3) that reduces damping-off disease in chilli and tomato nurseries. Journal of Natural Products: 70 6, 941-947

Bode,H.B.; Müller,Rolf*; (2007). Secondary Metabolism in Myxobacteria.: Myxobacteria: Multicellularity and Differentiation. Whitmorth,D.E.; (Ed.). Washington D.C. : ASM Press, 259-282

Kopp,M.; Rupprath,C.; Irschik,Herbert*; Bechthold,A.; Elling,L.; Müller,Rolf; (2007). SorF: a glycosyltransferase with promiscuous donor substrate specifity in vitro. ChemBioChem: 8, 813-819

Frank,B.; Knauber,J.; Steinmetz,Heinrich*; Scharfe,Maren*; Blöcker,Helmut*; Beyer,S.; Müller,Rolf*; (2007). Spiroketal polyketide formation in Sorangium: Identification and analysis of the biosynthetic gene cluster for the highly cytotoxic spirangienes. Chemistry and Biology: 114 2, 221-233

Menche,Dirk*; Hassfeld,J.; Steinmetz,Heinrich*; Huss,M.; Wieczorek,H.; Sasse,Florian*; (2007). The first hydroxylated archazolid from the myxobacterium Cystobacter violaceus : Isolation, structural elucidation and V-ATPase inhibition. The Journal of Antibiotics: 60 5, 328-331

Irschik,Herbert*; Reichenbach,Hans*; Höfle,Gerhard*; Jansen,Rolf*; (2007). The Thuggacins, novel antibacterial macrolides from Sorangium cellulosum acting against selected Gram-positive bacteria. Production, antimicrobial activity and mechanism of action. Journal of Antibiotics: 60, 733-738

Steinmetz,Heinrich*; Irschik,Herbert*; Kunze,Brigitte*; Reichenbach,Hans*; Höfle,Gerhard*; Jansen,Rolf*; (2007). Thuggacins, macrolide antibiotics active against Mycobacterium tuberculosis : isolation from myxobacteria, structure elucidation, conformation analysis and biosynthesis. Chemisty - A European Journal: 13 20, 5822-5832

Müller,Rolf*; Gerth,Klaus*; (2006). Development of simple media which allow investigations into the global regulation of chivosazol biosynthesis with Sorangium cellulosum So ce56. Journal of Biotechnology: 121, 192-200

Wenzel,S.C.; Gross,F.; Zhang,Y.; Fu,J.; Stewart,A.F.; Müller,Rolf*; (2005). Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering. Chemistry and Biology: 12 3, 349-356

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21.05.2012